Human IL-4 Quantikine ELISA Kit

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP

Human IL-4 Quantikine ELISA Kit Summary

• Background: The Quantikine Human IL-4 Immunoassay is a 4.5 hour solid phase ELISA designed to measure IL-4 levels in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human IL-4 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant human IL-4 accurately. Results obtained using natural human IL-4 sh...owed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human IL-4.
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• Specificity: Natural and recombinant human IL-4
• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: IL4

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-4 Quantikine ELISA Kit

• B cell growth factor 1
• BCDF
• B-cell stimulatory factor 1
• BCGF1
• BCGF-1
• binetrakin
• BSF1
• BSF-1
• IL4
• IL-4
• IL-4B_cell stimulatory factor 1
• IL4E12
• interleukin 4
• interleukin-4
• Lymphocyte stimulatory factor 1
• MGC79402
• pitrakinra

Background

IL-4 (Interleukin-4) is a cytokine that is primarily expressed by Th2-biased CD4+ T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG4 and IgE in human B cells, acquisition of the Th2 phenotype by naïve CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL-4 plays a dominant role in the development of allergic inflammation and asthma. The type I receptor for IL-4, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 R? and the common ? chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and -21). The type II receptor on nonhematopoietic cells consists of IL-4 R? and IL-13 R?1. The type II receptor also transduces IL-13 mediated signals.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for IL-4 (D4050)(75)

Publications using D4050

• Arita, K;Tao, H;Crowe, P;Thacher, S;Otake, S;Kobayashi, K;Ebihara, S;Okamoto, Y;Katsuda, Y;Yamaguchi, T;Matsushita, M; Pharmacological Properties of JTE-151; A Novel Orally Available ROR? Antagonist That Suppresses Th17 Cell-Related Responses <i>in Vitro</i> and <i>in Vivo</i> Biological and Pharmaceutical Bulletin 2024-12-12 [PMID: 39675971] (Human)
• Szyma?ska, B;Knysz, B;Ciep?ucha, H;Piwowar, A; Assessment of Metabolic, Inflammatory, and Immunological Disorders Using a New Panel of Plasma Parameters in People Living with HIV Undergoing Antiretroviral Therapy-A Retrospective Study Journal of clinical medicine 2024-08-05 [PMID: 39124846] (Human)
• Freedman, P;Schock, B;O'Reilly, S; The Novel Cytokine Interleukin-41/Meteorin-like Is Reduced in Diffuse Systemic Sclerosis Cells 2024-07-17 [PMID: 39056787] (Human)
• Kutuk, MO;Tufan, AE;Kilicaslan, F;Gokcen, C;Aksu, GG;Yektas, C;Kandemir, H;Celik, F;Mutluer, T;Buber, A;Karadag, M;Coban, N;Coskun, S;Hangul, Z;Altintas, E;Acikbas, U;Giray, A;Aka, Y;Basturk, B;Kutuk, O; Cytokine expression profiles in children and adolescents with tic disorders Scientific reports 2024-07-02 [PMID: 38956051] (Human)
• Ao, L;Shi, J;Gan, J;Yu, W;Du, H; Effects of dexmedetomidine and ketorolac applied for patient?controlled analgesia on the balance of Th1/Th2 and level of VEGF in patients undergoing laparoscopic surgery for cervical cancer: A randomized controlled trial Oncology letters 2024-08-01 [PMID: 38939623] (Human)
• Kim, H;Park, HH;Kim, HN;Seo, D;Hong, KS;Jang, JG;Seo, EU;Kim, IY;Jeon, SY;Son, B;Cho, SW;Kim, W;Ahn, JH;Lee, W; The TOX-RAGE axis mediates inflammatory activation and lung injury in severe pulmonary infectious diseases Proceedings of the National Academy of Sciences of the United States of America 2024-06-25 [PMID: 38900789] (Human)
• Scovino, AM;Dahab, EC;Diniz-Lima, I;de Senna Silveira, E;Barroso, SPC;Cardoso, KM;Nico, D;Makhoul, GJ;da Silva-Junior, EB;Freire-de-Lima, CG;Freire-de-Lima, L;Fonseca, LMD;Valente, N;Nacife, V;Machado, A;Araújo, M;Vieira, GF;Pauvolid-Corrêa, A;Siqueira, M;Morrot, A; A Comparative Analysis of Innate Immune Responses and the Structural Characterization of Spike from SARS-CoV-2 Gamma Variants and Subvariants Microorganisms 2024-04-02 [PMID: 38674664] (Human)
• Tomaszewski, M;Mertowska, P;Janczewska, M;Stycze?, A;Mertowski, S;Jonas, K;Grywalska, E;Kope?, G; In the Search for Biomarkers of Pulmonary Arterial Hypertension, Are Cytokines IL-2, IL-4, IL-6, IL-10, and IFN-Gamma the Right Indicators to Use? International journal of molecular sciences 2023-09-05 [PMID: 37761997] (Human)
• Y Song, J Jiang, Q Bai, S Liu, Y Zhang, C Xu, H Piao, L Li, G Yan Gene expression profiles and bioinformatics analysis in lung samples from ovalbumin-induced asthmatic mice BMC pulmonary medicine, 2023-02-02;23(1):50. 2023-02-02 [PMID: 36726128] (Mouse)
• Q D'Arcy, M Gharaee-Ke, A Zhilin-Rot, JA Macoska The IL-4/IL-13 signaling axis promotes prostatic fibrosis PLoS ONE, 2022-10-06;17(10):e0275064. 2022-10-06 [PMID: 36201508] (Human)
• E De Corso, S Baroni, S Settimi, ME Onori, RF Mastrapasq, E Troiani, G Moretti, D Lucchetti, M Corbò, C Montuori, A Cantiani, DP Porru, S Lo Verde, GA Di Bella, C Caruso, J Galli Sinonasal Biomarkers Defining Type 2-High and Type 2-Low Inflammation in Chronic Rhinosinusitis with Nasal Polyps Journal of personalized medicine, 2022-07-29;12(8):. 2022-07-29 [PMID: 36013200] (Human)
• W Singhatana, S Kitpakorns, M Toso, P Pavasant IFNgamma-primed periodontal ligament cells regulate T-cell responses via IFNgamma-inducible mediators and ICAM-1-mediated direct cell contact Royal Society open science, 2022-07-27;9(7):220056. 2022-07-27 [PMID: 35911203] (Human)
• N Jirapongwa, S Thongchot, W Chiraphapp, T Chieochans, D Sa-Nguanra, M Warnnissor, P Thuwajit, PT Yenchitsom, C Thuwajit Mesothelin?specific T cell cytotoxicity against triple negative breast cancer is enhanced by 40s ribosomal protein subunit 3?treated self?differentiated dendritic cells Oncology reports, 2022-05-26;48(1):. 2022-05-26 [PMID: 35616135] (Human)
• S Luo, R Wu, Q Li, G Zhang Epigenetic Regulation of IFI44L Expression in Monocytes Affects the Functions of Monocyte-Derived Dendritic Cells in Systemic Lupus Erythematosus Journal of Immunology Research, 2022-05-10;2022(0):4053038. 2022-05-10 [PMID: 35592687] (Human)
• WS Khalaf, MRA Mahmoud, WF Elkhatib, HR Hashem, WE Soliman Phenotypic characterization of NKT-like cells and evaluation of specifically related cytokines for the prediction of unexplained recurrent miscarriage Heliyon, 2021-11-16;7(11):e08409. 2021-11-16 [PMID: 34849421] (Human)
• Limo Gao, Wenmin Jiang, Haiying Liu, Zhiheng Chen, Yanhui Lin Receptor‑selective interleukin‑4 mutein attenuates laser‑induced choroidal neovascularization through the regulation of macrophage polarization in mice Experimental and Therapeutic Medicine 2021-09-27 [PMID: 34659513] (Mouse)
• A Kuzumi, A Yoshizaki, KM Matsuda, H Kotani, Y Norimatsu, M Fukayama, S Ebata, T Fukasawa, A Yoshizaki-, Y Asano, K Morikawa, Y Kazoe, K Mawatari, T Kitamori, S Sato Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis Nature Communications, 2021-10-12;12(1):5947. 2021-10-12 [PMID: 34642338] (Human)
• B Sikora, A Skubis-Sik, A Prusek, J Gola Paracrine activity of adipose derived stem cells on limbal epithelial stem cells Scientific Reports, 2021-10-07;11(1):19956. 2021-10-07 [PMID: 34620960] (Human)
• R Maglie, F Ugolini, F De Logu, R Nassini, S Simi, P Nardiello, E Pasqualini, G Baroni, E Del Bianco, D Massi, E Antiga Over-expression of Th2-related molecules in the skin of patients with eosinophilic dermatosis of hematologic malignancy Journal of the American Academy of Dermatology, 2021-07-13;0(0):. 2021-07-13 [PMID: 34265409] (Human)
• L Avila, ML Neves, AR Abreu, CR Fiuza, L Fukusawa, N Meziat-Fil, AR Soares San Cognitive functional therapy (CFT) compared with core training exercise (CTE) in patients with failed back surgery syndrome (FBSS): A study protocol for a randomized controlled trial Journal of bodywork and movement therapies, 2020-09-14;26(0):428-434. 2020-09-14 [PMID: 33992278] (Human)
• R Li, Y Li, X Dong Preconditioning mesenchymal stromal cells with flagellin enhances the anti?inflammatory ability of their secretome against lipopolysaccharide?induced acute lung injury Molecular Medicine Reports, 2020-07-28;0(0):. 2020-07-28 [PMID: 32945411] (Human)
• Gao Y, Sun W, Cha X, Wang H 'Psoriasis 1' reduces T‑lymphocyte‑mediated inflammation in patients with psoriasis by inhibiting vitamin D receptor‑mediated STAT4 inactivation. Int J Mol Med, 2020-08-06;46(4):1538-1550. 2020-08-06 [PMID: 32945358] (Human)
• HH Park, HN Kim, H Kim, Y Yoo, H Shin, EY Choi, JS Bae, W Lee Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia Sci Adv, 2020-07-31;6(31):. 2020-07-31 [PMID: 32937590] (Human)
• A Sa?kowska, K Kara?, I Karwaciak, A Walczak-Dr, M Krawczyk, M Sobalska-K, J Dastych, M Ratajewski Identification of Novel Molecular Markers of Human Th17 Cells Cells, 2020-07-03;9(7):. 2020-07-03 [PMID: 32635226] (Human)
• MO Kutuk, E Tufan, C Gokcen, F Kilicaslan, M Karadag, T Mutluer, C Yektas, N Coban, H Kandemir, A Buber, S Coskun, U Acikbas, G Guler, Z Topal, F Celik, E Altintas, A Giray, Y Aka, O Kutuk Cytokine expression profiles in Autism spectrum disorder: A multi-center study from Turkey Cytokine, 2020-06-18;133(0):155152. 2020-06-18 [PMID: 32563959] (Human)
• M Al-Ayed, K Alshaybari, D Alshehri, A Jamaan, I Nasser, H Alaamri, W Alaseeri, AA Mahfouz, S Ali Alsare, AM Asaad, A Ali Magzou, MA Qureshi, MH Shalayel Obesity and childhood asthma in male schoolchildren in Saudi Arabia: Is there a role for leptin, interleukin-4, interleukin-5, and interleukin-21? Ann Saudi Med, 2019-10-03;39(5):295-301. 2019-10-03 [PMID: 31580718] (Human)
• H Yu, S Cui, Y Mei, Q Li, L Wu, S Duan, G Cai, H Zhu, B Fu, L Zhang, Z Feng, X Chen Mesangial Cells Exhibit Features of Antigen-Presenting Cells and Activate CD4+ T Cell Responses J Immunol Res, 2019-06-17;2019(0):2121849. 2019-06-17 [PMID: 31317046] (Human)
• T Sun, M Ju, X Dai, H Dong, W Gu, Y Gao, R Fu, X Liu, Y Huang, W Liu, Y Chi, W Wang, H Li, Y Zhou, L Shi, R Yang, L Zhang Multilevel defects in the hematopoietic niche in essential thrombocythemia Haematologica, 2019-07-09;0(0):. 2019-07-09 [PMID: 31289202] (Human)
• FN Osuji, CC Onyenekwe, JE Ahaneku, NR Ukibe The effects of highly active antiretroviral therapy on the serum levels of pro-inflammatory and anti-inflammatory cytokines in HIV infected subjects J. Biomed. Sci., 2018-12-03;25(1):88. 2018-12-03 [PMID: 30501642] (Human)
• AE Stanciu, MM Stanciu, RG Vatasescu NT-proBNP and CA 125 levels are associated with increased pro-inflammatory cytokines in coronary sinus serum of patients with chronic heart failure Cytokine, 2018-08-08;111(0):13-19. 2018-08-08 [PMID: 30098475] (Human)
• A Rajamanick, S Munisankar, Y Bhootra, CK Dolla, K Thiruvenga, TB Nutman, S Babu Altered levels of memory T cell subsets and common ?c cytokines in Strongyloides stercoralis infection and partial reversal following anthelmintic treatment PLoS Negl Trop Dis, 2018-05-24;12(5):e0006481. 2018-05-24 [PMID: 29795573] (Human)
• P Sowa, M Misiolek, B Pasinski, G Bartosz, M Soszynski, M Adamczyk-S, I Sadowska-B Oxidative Stress Markers Patients with Parotid Gland Tumors: A Pilot Study Biomed Res Int, 2018-01-30;2018(0):4340871. 2018-01-30 [PMID: 29651432] (Human)
• D Bayik, D Tross, DM Klinman Factors Influencing the Differentiation of Human Monocytic Myeloid-Derived Suppressor Cells Into Inflammatory Macrophages Front Immunol, 2018-03-26;9(0):608. 2018-03-26 [PMID: 29632539] (Human)
• G Jordakieva, I Grabovac, E Valic, KE Schmidt, A Graff, A Schuster, K Hoffmann-S, C Oberhuber, O Scheiner, A Goll, J Godnic-Cva Occupational exposure to ultrafine particles in police officers: no evidence for adverse respiratory effects J Occup Med Toxicol, 2018-02-03;13(0):5. 2018-02-03 [PMID: 29434649] (ELISA Capture, Human)
• NA Johdi, L Mazlan, I Sagap, R Jamal Profiling of cytokines, chemokines and other soluble proteins as a potential biomarker in colorectal cancer and polyps Cytokine, 2017-07-06;99(0):35-42. 2017-07-06 [PMID: 28689023] (Human)
• VR Ribeiro, M Romao-Veig, GG Romagnoli, ML Matias, PR Nunes, VTM Borges, JC Peracoli, MTS Peracoli Association between cytokine profile and transcription factors produced by T cells subsets in early and late-onset preeclampsia Immunology, 2017-06-19;0(0):. 2017-06-19 [PMID: 28502089] (Human)
• Almut Meyer-Bahl Human Basophils Modulate Plasma Cell Differentiation and Maturation J. Immunol., 2016-11-16;0(0):. 2016-11-16 [PMID: 27852746] (Human)
• Bu X, Zhang T, Wang C, Ren T, Wen Z IL-33 reflects dynamics of disease activity in patients with autoimmune hemolytic anemia by regulating autoantibody production. J Transl Med, 2015-12-16;13(0):381. 2015-12-16 [PMID: 26675669] (Human)
• Magrinelli F, Briani C, Romano M, Ruggero S, Toffanin E, Triolo G, Peter G, Praitano M, Lauriola M, Zanette G, Tamburin S The Association between Serum Cytokines and Damage to Large and Small Nerve Fibers in Diabetic Peripheral Neuropathy. J Diabetes Res, 2015-04-16;2015(0):547834. 2015-04-16 [PMID: 25961054] (Human)
• Aderhold C, Grobschmidt G, Sauter A, Faber A, Hormann K, Schultz J Interleukin 4, interleukin 6 and osteopontin-serological markers of head and neck malignancy in primary diagnostics: A pilot study. Oncol Lett, 2014-07-04;8(3):1112-1118. 2014-07-04 [PMID: 25120668] (Human)
• Zhang Y, Chen H, Sun C, Wang H, Liu M, Li Y, Nie X, Du M, Li D, Zhang J Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy. PLoS ONE, 2014-06-16;9(6):e99612. 2014-06-16 [PMID: 24932916] (Human)
• Jun H, Weinstein D, Lee Y, Mansfield B, Chou J Molecular mechanisms of neutrophil dysfunction in glycogen storage disease type Ib. Blood, 2014-02-24;123(18):2843-53. 2014-02-24 [PMID: 24565827] (Human)
• Biancheri P, Di Sabatino A, Ammoscato F, Facciotti F, Caprioli F, Curciarello R, Hoque S, Ghanbari A, Joe-Njoku I, Giuffrida P, Rovedatti L, Geginat J, Corazza G, MacDonald T Absence of a role for interleukin-13 in inflammatory bowel disease. Eur J Immunol, 2014-02-01;44(2):370-85. 2014-02-01 [PMID: 24338958] (Human)
• Hussein Y, El-Shal A, Rezk N, Abdel Galil S, Alzahrani S Influence of interleukin-4 gene polymorphisms and interleukin-4 serum level on susceptibility and severity of rheumatoid arthritis in Egyptian population. Cytokine, 2013-02-06;61(3):849-55. 2013-02-06 [PMID: 23394902] (Human)
• Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P, Exley MA, Anderson KC, Munshi NC HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells. Leukemia, 2010-11-19;25(1):161-8. 2010-11-19 [PMID: 21102427] (Human)
• Beziat V, Nguyen S, Exley M, Achour A, Simon T, Chevallier P, Sirvent A, Vigouroux S, Debre P, Rio B, Vieillard V, Lubrano-Berthelier C, Alatrakchi N Shaping of iNKT cell repertoire after unrelated cord blood transplantation. Clin. Immunol., 2010-02-13;135(3):364-73. 2010-02-13 [PMID: 20153980] (Human)
• Mabilleau G, Sabokbar A Interleukin-32 promotes osteoclast differentiation but not osteoclast activation. PLoS ONE, 2009-01-12;4(1):e4173. 2009-01-12 [PMID: 19137064] (Human)
• Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, Ring J, Traidl-Hoffmann C, Albanesi C, Cavani A IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. J. Allergy Clin. Immunol., 2008-12-03;123(1):59-66.e4. 2008-12-03 [PMID: 19056110] (Human)
• Yokoi T, Amakawa R, Tanijiri T, Sugimoto H, Torii Y, Amuro H, Son Y, Tajima K, Liu YJ, Ito T, Fukuhara S Mycobacterium bovis Bacillus Calmette-Guerin suppresses inflammatory Th2 responses by inducing functional alteration of TSLP-activated dendritic cells. Int. Immunol., 2008-08-13;20(10):1321-9. 2008-08-13 [PMID: 18703465] (Human)
• Miller R, Sadhukhan R, Wu C Development of an in vitro potency bioassay for therapeutic IL-13 antagonists: the A-549 cell bioassay. J. Immunol. Methods, 2008-03-07;334(1):134-41. 2008-03-07 [PMID: 18355834] (Human)
• Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells. Eur. J. Immunol., 2008-04-01;38(4):1012-23. 2008-04-01 [PMID: 18350544] (Human)
• Miller M, Ramsdell J, Friedman PJ, Cho JY, Renvall M, Broide DH Computed tomographic scan-diagnosed chronic obstructive pulmonary disease-emphysema: eotaxin-1 is associated with bronchodilator response and extent of emphysema. J. Allergy Clin. Immunol., 2007-11-01;120(5):1118-25. 2007-11-01 [PMID: 17983873] (Human)
• Vidyarani M, Selvaraj P, Jawahar MS, Narayanan PR 1, 25 Dihydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis. Cytokine, 2007-10-29;40(2):128-34. 2007-10-29 [PMID: 17911026] (Human)
• Lin YL, Liang YC, Chiang BL Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells. J. Leukoc. Biol., 2007-08-30;82(6):1473-80. 2007-08-30 [PMID: 17761954] (Human)
• Sadeghi M, Susal C, Daniel V, Naujokat C, Zimmermann R, Huth-Kuhne A, Opelz G Short communication: decreasing soluble CD30 and increasing IFN-gamma plasma levels are indicators of effective highly active antiretroviral therapy. AIDS Res. Hum. Retroviruses, 2007-07-01;23(7):886-90. 2007-07-01 [PMID: 17678471] (Human)
• Karrar A, Broome U, Uzunel M, Qureshi AR, Sumitran-Holgersson S Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction. Gut, 2006-07-13;56(2):243-52. 2006-07-13 [PMID: 16840505] (Human)
• Yoshikawa H, Sato K, Edahiro S, Furukawa Y, Maruta T, Iwasa K, Watanabe H, Takaoka S, Suzuki Y, Takamori M, Yamada M Elevation of IL-12 p40 and its antibody in myasthenia gravis with thymoma. J. Neuroimmunol., 2006-03-29;175(1):169-75. 2006-03-29 [PMID: 16574246] (Human)
• Ehling A, Schaffler A, Herfarth H, Tarner IH, Anders S, Distler O, Paul G, Distler J, Gay S, Scholmerich J, Neumann E, Muller-Ladner U The potential of adiponectin in driving arthritis. J. Immunol., 2006-04-01;176(7):4468-78. 2006-04-01 [PMID: 16547285] (Human)
• Hartl D, Latzin P, Zissel G, Krane M, Krauss-Etschmann S, Griese M Chemokines indicate allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. Am. J. Respir. Crit. Care Med., 2006-03-16;173(12):1370-6. 2006-03-16 [PMID: 16543550] (Human)
• Sheikine Y, Olsen B, Gharizadeh B, Jatta K, Tornvall P, Ghaderi M Influence of eotaxin 67G>A polymorphism on plasma eotaxin concentrations in myocardial infarction survivors and healthy controls. Atherosclerosis, 2006-02-28;189(2):458-63. 2006-02-28 [PMID: 16510147] (Human)
• Sheikine Y, Bang CS, Nilsson L, Samnegard A, Hamsten A, Jonasson L, Eriksson P, Sirsjo A Decreased plasma CXCL16/SR-PSOX concentration is associated with coronary artery disease. Atherosclerosis, 2005-12-27;188(2):462-6. 2005-12-27 [PMID: 16378611] (Human)
• Kristjansson S, Bjarnarson SP, Wennergren G, Palsdottir AH, Arnadottir T, Haraldsson A, Jonsdottir I Respiratory syncytial virus and other respiratory viruses during the first 3 months of life promote a local TH2-like response. J. Allergy Clin. Immunol., 2005-10-01;116(4):805-11. 2005-10-01 [PMID: 16210054] (Human)
• Mistchenko AS, Fornari MC, Viegas M, Barrero PR, Diez RA Detection of interleukin 10 in cerebrospinal fluid of patients with subacute sclerosing panencephalitis. J. Neurovirol., 2005-02-01;11(1):66-9. 2005-02-01 [PMID: 15804961] (Human)
• Takei M, Umeyama A, Arihara S, Matsumoto H Effect of piceatannol in human monocyte-derived dendritic cells in vitro. J Pharm Sci, 2005-05-01;94(5):974-82. 2005-05-01 [PMID: 15793803] (Human)
• Huang JL, Huang J, Duan ZH, Wei J, Min J, Luo XH, Li JG, Tan WP, Wu LZ, Liu RY, Li Y, Shao J, Huang BJ, Zeng YX, Huang W Th2 predominance and CD8+ memory T cell depletion in patients with severe acute respiratory syndrome. Microbes Infect., 2005-02-24;7(3):427-36. 2005-02-24 [PMID: 15784184] (Human)
• Ciprandi G, Tosca MA, Milanese M, Caligo G, Ricca V Cytokines evaluation in nasal lavage of allergic children after Bacillus clausii administration: a pilot study. Pediatr Allergy Immunol, 2004-04-01;15(2):148-51. 2004-04-01 [PMID: 15059191] (Human)
• Basu S, Aballa TC, Ferrell SM, Lynne CM, Brackett NL Inflammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries. J. Androl., 2004-03-01;25(2):250-4. 2004-03-01 [PMID: 14760011] (Human)
• Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS. J. Leukoc. Biol., 2003-05-01;73(5):584-90. 2003-05-01 [PMID: 12714572] (Human)
• D'Ambrosio D Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gamma delta T lymphocytes. Eur. J. Immunol., 2002-10-01;32(10):2934-43. 2002-10-01 [PMID: 12355447] (Human)
• Marme A, Strauss G, Bastert G, Grischke EM, Moldenhauer G Intraperitoneal bispecific antibody (HEA125xOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma. Int. J. Cancer, 2002-09-10;101(2):183-9. 2002-09-10 [PMID: 12209996] (Human)
• Cotler SJ, Reddy KR, McCone J, Wolfe DL, Liu A, Craft TR, Ferris MW, Conrad AJ, Albrecht J, Morrissey M, Ganger DR, Rosenblate H, Blatt LM, Jensen DM, Taylor MW An analysis of acute changes in interleukin-6 levels after treatment of hepatitis C with consensus interferon. J. Interferon Cytokine Res., 2001-12-01;21(12):1011-9. 2001-12-01 [PMID: 11798458] (Human)
• Albanesi C, Scarponi C, Sebastiani S, Cavani A, Federici M, Sozzani S, Girolomoni G A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases. J. Leukoc. Biol., 2001-10-01;70(4):617-23. 2001-10-01 [PMID: 11590199] (Human)
• Kadowaki N, Antonenko S, Lau JY, Liu YJ Natural interferon alpha/beta-producing cells link innate and adaptive immunity. J. Exp. Med., 2000-07-17;192(2):219-26. 2000-07-17 [PMID: 10899908] (Human)
• Petitto JM, Leserman J, Perkins DO, Stern RA, Silva SG, Gettes D, Zheng B, Folds JD, Golden RN, Evans DL High versus low basal cortisol secretion in asymptomatic, medication-free HIV-infected men: differential effects of severe life stress on parameters of immune status. Behav Med, 2000-01-01;25(4):143-51. 2000-01-01 [PMID: 10789020] (Human)
• Manetti , R, Parronchi , P, Giudizi , M G, Piccinni , M P, Maggi , E, Trinchieri , G, Romagnani , S Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J Exp Med, 1993-04-01;177(4):1199-204. 1993-04-01 [PMID: 8096238] (Human)

Bioinformatics

• Gene Symbol: IL4