Human IL-10 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human IL-10 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: IL10

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-10 DuoSet ELISA, 15 Plate

• CSIF
• CSIFMGC126450
• Cytokine synthesis inhibitory factor
• GVHDS
• IL10
• IL-10
• IL10A
• IL-10MGC126451
• interleukin 10
• interleukin-10
• TGIF

Background

Interleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor (CSIF), is the charter member of the IL-10 alpha -helical cytokine family that also includes IL-19, IL-20, IL-22, IL-24, and IL-26/AK155 (1-3). IL-10 is secreted by many activated hematopoietic cell types as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts. Whereas human IL-10 is active on mouse cells, mouse IL-10 does not act on human cells (4, 5). Mature human IL-10 shares 86% amino acid sequence identity with equine IL-10 and 72% - 80% with bovine, canine, feline, guinea pig, mouse, ovine, porcine, and rat IL-10. It contains two intrachain disulfide bridges and is expressed as a 36 kDa noncovalently-associated homodimer (4, 6, 7). 

IL-10 mediates its biological activities through a heteromeric receptor complex composed of the type II cytokine receptor subunits IL-10 R alpha and IL-10 R beta . IL-10 R alpha is a 110 kDa transmembrane glycoprotein that is expressed on lymphocytes, NK cells, macrophages, monocytes, astrocytes, intestinal epithelial cells, cytotrophoblasts, and activated hepatic stellate cells (8-13), while the 75 kDa transmembrane IL-10 R beta is widely expressed (14, 15). The IL-10 dimer binds to two IL-10 R alpha chains, triggering recruitment of two IL-10 R beta chains (14, 15). IL-10 R beta does not bind IL-10 directly but is required for signal transduction. IL-10 R beta also associates with IL-20 R alpha , IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29 (16-18). 

The involvement of IL-10 in immunoregulation includes both suppressive and stimulatory effects. It functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells (19-21) and by promoting the development of M2 macrophages (21). Its expression by immunosuppressive regulatory T cells (Treg) and regulatory B cells is important for Treg proliferation (19). Within a tumor microrenvironment, however, IL-10 inhibits the expansion of Treg as well as myeloid-derived suppressor cells (22, 23). IL-10 induces the intratumoral accumulation and activation of CD8+ T cells (24, 25). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation (19) and promoting muscle regeneration after injury (21), but it also contributes to the persistence of viral infections (26). The levels of IL-10 are elevated in Sjogren's syndrome (saliva), primary CNS lymphoma (cerebrospinal fluid), and ovarian cancer (serum and ascites) (27-29). Its levels are decreased in the serum in patients with recurrent heart attacks or during preeclampsia and also in the seminal fluid of infertile men (30-32).

Publications for IL-10 (DY217B)(215)

Publications using DY217B

• Abdel-Raoof Fouda, M;Abdel-Wahhab, M;Abdelkader, AE;Ibrahim, ME;Elsheikh, TA;Aldeweik, HM;Elfeky, N; Effect of gut microbiota changes on cytokines IL-10 and IL-17 levels in liver transplantation patients BMC infectious diseases 2025-01-30 [PMID: 39885417] (Human)
• Tucker, RM;Kim, N;Gurzell, E;Mathi, S;Chavva, S;Senthilkumar, D;Bartunek, O;Fenton, KC;Herndon-Fenton, SJ;Cardino, VN;Cooney, GM;Young, S;Fenton, JI; Commonly Used Dose of Montmorency Tart Cherry Powder Does Not Improve Sleep or Inflammation Outcomes in Individuals with Overweight or Obesity Nutrients 2024-11-28 [PMID: 39683518] (Human)
• Kumar, N;Mattoo, SS;Sanghvi, S;Ellendula, MP;Mahajan, S;Planner, C;Bednash, JS;Khan, M;Ganesan, LP;Singh, H;Lafuse, WP;Wozniak, DJ;Rajaram, MVS; Pseudomonas aeruginosa- mediated cardiac dysfunction is driven by extracellular vesicles released during infection bioRxiv : the preprint server for biology 2024-11-25 [PMID: 39651123] (Human)
• Bekirian, C;Valsecchi, I;Bachellier-Bassi, S;Scandola, C;Guijarro, JI;Chauvel, M;Mourer, T;Gow, NAR;Aimanianda, VK;d'Enfert, C;Fontaine, T; ?-1,6-Glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall eLife 2024-12-05 [PMID: 39636210] (Human)
• Moura-Maia, MS;Brill, B;Paula-Vieira, RHR;Ramos-Gomes, NV;Melamed, D;Silva-Reis, A;Wolpp, ETR;Moreira-Silva, NN;Bella, YF;Vieira, RP; Low Caloric Intake Confers Cardiovascular Protection and Improves Functional Capacity Without Affecting Immunological Response in Sedentary Older Adults Nutrients 2024-10-29 [PMID: 39519510] (Human)
• Flores-Gomez, D;Hobo, W;van Ens, D;Kessler, EL;Novakovic, B;Schaap, NPM;Rijnen, WHC;Joosten, LAB;Netea, MG;Riksen, NP;Bekkering, S; Interleukin-1? induces trained innate immunity in human hematopoietic progenitor cells in vitro Stem cell reports 2024-09-25 [PMID: 39515317] (Human)
• Tan, KBC;Alexander, HD;Linden, J;Murray, EK;Gibson, DS; Anti-inflammatory effects of phytocannabinoids and terpenes on inflamed Tregs and Th17 cells in vitro Experimental and molecular pathology 2024-08-28 [PMID: 39208564] (Human)
• Dellière, S;Chauvin, C;Wong, SSW;Gressler, M;Possetti, V;Parente, R;Fontaine, T;Krüger, T;Kniemeyer, O;Bayry, J;Carvalho, A;Brakhage, AA;Inforzato, A;Latgé, JP;Aimanianda, V; Interplay between host humoral pattern recognition molecules controls undue immune responses against Aspergillus fumigatus Nature communications 2024-08-14 [PMID: 39138196] (Human)
• Bachmann, V;Schädel, P;Westhoff, J;Peri?, M;Schömberg, F;Skaltsounis, AL;Höppener, S;Pantsar, T;Fischer, D;Vilotijevi?, I;Werz, O; Bromo-substituted indirubins for inhibition of protein kinase-mediated signalling involved in inflammatory mediator release in human monocytes Bioorganic chemistry 2024-05-23 [PMID: 38838619] (Human)
• Egawa, Y;Higuchi, T;Hashida, Y;Ueno, K;Kojima, K;Daibata, M; Novel paired CD13-negative (MT-50.1) and CD13-positive (MT-50.4) HTLV-1-infected T-cell lines with differential regulatory T cell-like activity Scientific reports 2024-05-31 [PMID: 38822041] (Human)
• Chen, KY;Sun, WL;Wu, SM;Feng, PH;Lin, CF;Chen, TT;Lu, YH;Ho, SC;Chen, YH;Lee, KY; Reduced Tolerogenic Program Death-Ligand 1-Expressing Conventional Type 1 Dendritic Cells Are Associated with Rapid Decline in Chronic Obstructive Pulmonary Disease Cells 2024-05-20 [PMID: 38786101] (Human)
• da Costa Teixeira, LA;Soares, LA;Lima, LP;Avelar, NCP;de Moura, JA;Leopoldino, AAO;Figueiredo, PHS;Parentoni, AN;Mendonça, VA;Lacerda, ACR; Cognitive function is associated with performance in time up and go test and with leptin blood levels in community-dwelling older women Scientific reports 2024-04-29 [PMID: 38684691] (Human)
• Chick, HM;Rees, ME;Lewis, ML;Williams, LK;Bodger, O;Harris, LG;Rushton, S;Wilkinson, TS; Using the Traditional Ex Vivo Whole Blood Model to Discriminate Bacteria by Their Inducible Host Responses Biomedicines 2024-03-25 [PMID: 38672079] (Human)
• Dos Santos, JC;Moreno, M;Teufel, LU;Chilibroste, S;Keating, ST;Groh, L;Domínguez-Andrés, J;Williams, DL;Ma, Z;Lowman, DW;Ensley, HE;Novakovic, B;Ribeiro-Dias, F;Netea, MG;Chabalgoity, JA;Joosten, LAB; Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity Cell reports 2024-03-07 [PMID: 38457336] (Human)
• Gaggioli, MR;Jones, AG;Panagi, I;Washington, EJ;Loney, RE;Muench, JH;Brennan, RG;Thurston, TLM;Ko, DC; A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory target gene expression bioRxiv : the preprint server for biology 2024-02-14 [PMID: 38405869] (Human)
• Augusto da Costa Teixeira, L;Rocha-Vieira, E;Aparecida Soares, L;Mota de Oliveira, F;Aparecida Oliveira Leopoldino, A;Netto Parentoni, A;Amaral Mendonça, V;Cristina Rodrigues Lacerda, A; The strong inverse association between plasma concentrations of soluble tumor necrosis factor receptors type 1 with adiponectin/leptin ratio in older women Cytokine 2024-01-27 [PMID: 38281360] (Human)
• Bo?kun, ?;Starosz, A;Kr?towska-Grunwald, A;Wasiluk, T;Walewska, A;Wierzbowska, A;Moniuszko, M;Grubczak, K; Effects of Combinatory In Vitro Treatment with Immune Checkpoint Inhibitors and Cytarabine on the Anti-Cancer Immune Microenvironment in De Novo AML Patients Cancers 2024-01-22 [PMID: 38275902] (Human)
• Tsai, HF;Tseng, CF;Liang, YL;Wu, PY;Huang, LY;Lin, YH;Lin, LH;Lin, CN;Hsu, KF; Downregulation of Salt-Inducible Kinase 3 Enhances CCL24 Activation in the Placental Environment with Preeclampsia International journal of molecular sciences 2023-12-22 [PMID: 38203391] (Human)
• De, M;Sukla, S;Bharatiya, S;Keshri, S;Roy, DG;Roy, S;Dutta, D;Saha, S;Ejazi, SA;Ravichandiran, V;Ali, N;Chatterjee, M;Chinnaswamy, S; IFN-?3 is induced by Leishmania donovani and can inhibit parasite growth in cell line models but not in the mouse model, while it shows a significant association with leishmaniasis in humans Infection and immunity 2024-01-09 [PMID: 38193711] (Human)
• Wu, WC;Shiu, C;Tong, TK;Leung, SO;Hui, CW; Suppression of NK Cell Activation by JAK3 Inhibition: Implication in the Treatment of Autoimmune Diseases Journal of immunology research 2023-12-08 [PMID: 38106519] (Human)
• Jalilian, E;Abolhasani-Zadeh, F;Afgar, A;Samoudi, A;Zeinalynezhad, H;Langroudi, L; Neutralizing tumor-related inflammation and reprogramming of cancer-associated fibroblasts by Curcumin in breast cancer therapy Scientific reports 2023-11-26 [PMID: 38008819] (Human)
• Han, X;Liu, L;Huang, S;Xiao, W;Gao, Y;Zhou, W;Zhang, C;Zheng, H;Yang, L;Xie, X;Liang, Q;Tu, Z;Yu, H;Fu, J;Wang, L;Zhang, X;Qian, L;Zhou, Y; RNA m6A methylation modulates airway inflammation in allergic asthma via PTX3-dependent macrophage homeostasis Nature communications 2023-11-13 [PMID: 37957139] (Human)
• Nikiforov, NG;Kirichenko, TV;Kubekina, MV;Chegodaev, YS;Zhuravlev, AD;Ilchuk, LA;Nikolaeva, MA;Arefieva, AS;Popov, MA;Verkhova, SS;Bagheri Ekta, M;Orekhov, AN; Macrophages derived from LPS-stimulated monocytes from individuals with subclinical atherosclerosis were characterized by increased pro-inflammatory activity Cytokine 2023-12-01 [PMID: 37918051] (Human)
• Gysan, MR;Milacek, C;Bal, C;Zech, A;Brugger, J;Milos, RI;Antoniewicz, L;Idzko, M;Gompelmann, D; Ventilatory support and inflammatory peptides in hospitalised patients with COVID-19: A prospective cohort trial PloS one 2023-11-02 [PMID: 37917760] (Human)
• Ren, J;Szombath, G;Vitale-Cross, L;Stroncek, DF;Robey, PG;Hajdara, A;Szalayova, I;Mayer, B;Martin, D;Mezey, E;Nemeth, K; The Potential Use of THP-1, a Monocytic Leukemia Cell Line, to Predict Immune-Suppressive Potency of Human Bone-Marrow Stromal Cells (BMSCs) In Vitro: A Pilot Study International journal of molecular sciences 2023-08-26 [PMID: 37686058] (Human)
• Meunier, M;Spillmann, A;Rousseaux, C;Schwamborn, K;Hanson, M; An oral cholera vaccine in the prevention and/or treatment of inflammatory bowel disease PloS one 2023-08-28 [PMID: 37639428] (Human)
• Kr?towska-Grunwald, A;Sawicka-?ukowska, M;Kowalska, M;Basaj, A;Krawczuk-Rybak, M;Moniuszko, M;Grubczak, K; Significance of Th17 and Treg in Treatment Efficacy and Outcome in Pediatric Acute Lymphoblastic Leukemia International journal of molecular sciences 2023-08-01 [PMID: 37569699] (Human)
• Grubczak, K;Starosz, A;Makowska, B;Parfienowicz, Z;Kr?towska, M;Naumnik, B;Moniuszko, M; The influence of calcitriol and methylprednisolone on podocytes function in minimal change disease in vitro model Scientific reports 2023-08-05 [PMID: 37543700] (Human)
• Park, GT;Lim, JK;Choi, EB;Lim, MJ;Yun, BY;Kim, DK;Yoon, JW;Hong, YG;Chang, JH;Bae, SH;Ahn, JY;Kim, JH; Transplantation of adipose tissue-derived microvascular fragments promotes therapy of critical limb ischemia Biomaterials research 2023-07-16 [PMID: 37455318] (Human)
• Malaga, W;Payros, D;Meunier, E;Frigui, W;Sayes, F;Pawlik, A;Orgeur, M;Berrone, C;Moreau, F;Mazères, S;Gonzalo-Asensio, J;Rengel, D;Martin, C;Astarie-Dequeker, C;Mourey, L;Brosch, R;Guilhot, C; Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli PLoS pathogens 2023-07-01 [PMID: 37450466] (Human)
• Isanejad, A;Nazari, S;Gharib, B;Motlagh, AG; Comparison of the effects of high-intensity interval and moderate-intensity continuous training on inflammatory markers, cardiorespiratory fitness, and quality of life in breast cancer patients Journal of sport and health science 2023-07-07 [PMID: 37423313] (Human)
• Fiorillo, A;Gallego, JJ;Casanova-Ferrer, F;Giménez-Garzó, C;Urios, A;Ballester, MP;Durbán, L;Rios, MP;Megías, J;San Miguel, T;Kosenko, E;Escudero-García, D;Benlloch, S;Felipo, V;Montoliu, C; Mild Cognitive Impairment Is Associated with Enhanced Activation of Th17 Lymphocytes in Non-Alcoholic Fatty Liver Disease International journal of molecular sciences 2023-06-20 [PMID: 37373554] (Human)
• da Costa Teixeira, LA;Avelar, NCP;Peixoto, MFD;Parentoni, AN;Santos, JMD;Pereira, FSM;Danielewicz, AL;Leopoldino, AAO;Costa, SP;Arrieiro, AN;Soares, LA;da Silva Lage, VK;Prates, ACN;Taiar, R;de Carvalho Bastone, A;Oliveira, VC;Oliveira, MX;Costa, HS;Nobre, JNP;Brant, FP;Duarte, TC;Figueiredo, PHS;Mendonça, VA;Lacerda, ACR; Inflammatory biomarkers at different stages of Sarcopenia in older women Scientific reports 2023-06-26 [PMID: 37365209] (Human)
• Ferreira, AV;Kostidis, S;Groh, LA;Koeken, VACM;Bruno, M;Baydemir, I;Kilic, G;Bulut, Ö;Andriopoulou, T;Spanou, V;Synodinou, KD;Gkavogianni, T;Moorlag, SJCFM;Charlotte de Bree, L;Mourits, VP;Matzaraki, V;Koopman, WJH;van de Veerdonk, FL;Renieris, G;Giera, M;Giamarellos-Bourboulis, EJ;Novakovic, B;Domínguez-Andrés, J; Dimethyl itaconate induces long-term innate immune responses and confers protection against infection Cell reports 2023-06-16 [PMID: 37330914] ( Human)
• Langgartner, D;Winkler, R;Brunner-Weisser, J;Rohleder, N;Jarczok, MN;Gündel, H;Weimer, K;Reber, SO; COVID-19 vaccination exacerbates ex vivo IL-6 release from isolated PBMCs Scientific reports 2023-06-12 [PMID: 37308487] (Human)
• Kislat, A;Olah, P;Kuchner, M;Gerber, PA;Schrader, J;Meller, S;Homey, B; The Endogenous Dual Retinoid Receptor Agonist Alitretinoin Exhibits Immunoregulatory Functions on Antigen-Presenting Cells International journal of molecular sciences 2023-06-02 [PMID: 37298605] (Human)
• Talalai, E;Gorobets, D;Halpert, G;Tsur, AM;Heidecke, H;Levy, Y;Watad, A;Blank, M;Michaelevski, I;Shoenfeld, Y;Amital, H; Functional IgG Autoantibodies against Autonomic Nervous System Receptors in Symptomatic Women with Silicone Breast Implants Cells 2023-05-30 [PMID: 37296631] (Human)
• M Shafiq, ZR Lone, AO Abdulkaree, G Kaur, S Navya, H Singh, K Jagavelu, K Hanif Inhibition of poly (ADP-ribose) Polymerase-1 (PARP-1) improves endothelial function in pulmonary hypertension Pulmonary pharmacology & therapeutics, 2023-02-25;0(0):102200. 2023-02-25 [PMID: 36842770] (Human)
• AJ Heires, D Samuelson, D Villageliu, TM Nordgren, DJ Romberger Agricultural dust derived bacterial extracellular vesicle mediated inflammation is attenuated by DHA Scientific Reports, 2023-02-16;13(1):2767. 2023-02-16 [PMID: 36797300] (Human)
• D Tortolani, C Di Meo, S Standoli, F Ciaramella, S Kadhim, E Hsu, C Rapino, M Maccarrone Rare Phytocannabinoids Exert Anti-Inflammatory Effects on Human Keratinocytes via the Endocannabinoid System and MAPK Signaling Pathway International Journal of Molecular Sciences, 2023-02-01;24(3):. 2023-02-01 [PMID: 36769042] (Human)
• M Nicolas, M Lasalo, S Chow, C Antheaume, K Huet, E Hnawia, GJ Guillemin, M Nour, M Matsui Anti-inflammatory activities of Coleus forsteri (formerly Plectranthus forsteri) extracts on human macrophages and chemical characterization Frontiers in Pharmacology, 2023-01-09;13(0):1081310. 2023-01-09 [PMID: 36699063] (Human)
• YY Chao, A Puhach, D Frieser, M Arunkumar, L Lehner, T Seeholzer, A Garcia-Lop, M van der Wa, S Fibi-Smeta, A Dietschman, T Sommermann, T ?ikovi?, L Taher, MS Gresnigt, SJ Vastert, F van Wijk, G Panagiotou, D Krappmann, O Gro beta , CE Zielinski Human TH17 cells engage gasdermin E pores to release IL-1alpha on NLRP3 inflammasome activation Nature Immunology, 2023-01-05;0(0):. 2023-01-05 [PMID: 36604548] (Human)
• H Asashima, S Mohanty, M Comi, WE Ruff, KB Hoehn, P Wong, J Klein, C Lucas, I Cohen, S Coffey, N Lele, L Greta, K Raddassi, O Chaudhary, A Unterman, B Emu, SH Kleinstein, RR Montgomery, A Iwasaki, CS Dela Cruz, N Kaminski, AC Shaw, DA Hafler, TS Sumida PD-1highCXCR5-CD4+ peripheral helper T�cells promote CXCR3+ plasmablasts in human acute viral infection Cell Reports, 2023-01-02;0(0):111895. 2023-01-02 [PMID: 36596303] (Human)
• AJ Eakin, T Ahmed, CM McGeough, S Drain, HD Alexander, GD Wright, PV Gardiner, D Small, AJ Bjourson, DS Gibson CD169+ Monocyte and Regulatory T Cell Subsets Are Associated with Disease Activity in Rheumatoid Arthritis Journal of personalized medicine, 2022-11-09;12(11):. 2022-11-09 [PMID: 36579595] (Human)
• LAC Teixeira, JM Dos Santos, AN Parentoni, LP Lima, TC Duarte, FP Brant, CDC Neves, FSM Pereira, NCP Avelar, AL Danielewic, AAO Leopoldino, SP Costa, AN Arrieiro, LA Soares, ACN Prates, JNP Nobre, A de Carvalh, VC de Oliveir, MX Oliveira, PH Scheidt Fi, HS Costa, V Amaral Men, R Taiar, AC Rodrigues Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study Journal of Clinical Medicine, 2022-12-02;11(23):. 2022-12-02 [PMID: 36498747] (Human)
• LU Teufel, CI van der Ma, V Klück, A Simons, A Hoischen, V Vernimmen, LAB Joosten, RJW Arts Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study Cytokine, 2022-12-05;162(0):156102. 2022-12-05 [PMID: 36476991] (Human)
• VC Capetini, BJ Quintanilh, DC de Oliveir, AH Nishioka, LA de Matos, LRP Ferreira, FM Ferreira, GR Sampaio, NMA Hassimotto, FM Lajolo, RA Fock, MM Rogero Blood orange juice intake modulates plasma and PBMC microRNA expression in overweight and insulin resistance women: impact on MAPK and NFkappaB signaling pathways The Journal of nutritional biochemistry, 2022-11-26;0(0):109240. 2022-11-26 [PMID: 36442716] (Human)
• JS Park, SC Yang, HY Jeong, SY Lee, JG Ryu, JW Choi, HY Kang, SM Kim, SH Hwang, ML Cho, SH Park EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis Arthritis Research & Therapy, 2022-11-17;24(1):254. 2022-11-17 [PMID: 36397156] (Human)
• B Saravi, Z Li, V Basoli, S Grad, S Häckel, CE Albers, M Alini, H Schmal, P Obid, G Lang In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells Cells, 2022-10-28;11(21):. 2022-10-28 [PMID: 36359814] (Human)
• F Reverchon, C Guillard, L Mollet, P Auzou, D Gosset, F Madouri, A Valéry, A Menuet, C Ozsancak, M Pallix-Guy, S Morisset-L T Lymphocyte Serotonin 5-HT7 Receptor Is Dysregulated in Natalizumab-Treated Multiple Sclerosis Patients Biomedicines, 2022-09-27;10(10):. 2022-09-27 [PMID: 36289679] (Human)
• D Kabelitz, M Zarobkiewi, M Heib, R Serrano, M Kunz, G Chitadze, D Adam, C Peters Signal strength of STING activation determines cytokine plasticity and cell death in human monocytes Scientific Reports, 2022-10-24;12(1):17827. 2022-10-24 [PMID: 36280676] (Human)
• H Wang, Y Li, Z Yue, Y Liu, Q Chen, D Hu, J Han Adipose-Derived Stem Cell Exosomes Inhibit Hypertrophic Scaring Formation by Regulating Th17/Treg Cell Balance BioMed Research International, 2022-10-12;2022(0):9899135. 2022-10-12 [PMID: 36277890] (Human)
• A Silva-Reis, MA Rodrigues, R Moraes-Fer, TG Gonçalves-, VH Souza-Palm, HC Aquino-San, ALL Bachi, LVF de Oliveir, RÁB Lopes-Mart, I Oliveira-S, R Albertini, CR Frison, RP Vieira Combined resistance and aerobic training improves lung function and mechanics and fibrotic biomarkers in overweight and obese women Frontiers in Physiology, 2022-09-07;13(0):946402. 2022-09-07 [PMID: 36160852] (Human)
• M Dubus, L Scomazzon, C Ledouble, J Braux, A Beljebbar, L Van Gulick, A Baldit, C Gorin, H Alem, N Bouland, M Britton, J Schiavi, TJ Vaughan, C Mauprivez, H Kerdjoudj Hybrid Mineral/Organic Material Induces Bone Bridging and Bone Volume Augmentation in Rat Calvarial Critical Size Defects Cells, 2022-09-14;11(18):. 2022-09-14 [PMID: 36139439] (Human)
• M Shafiq, ZR Lone, P Bharati, S Mahapatra, P Rai, N Khandelwal, AN Gaikwad, K Jagavelu, K Hanif Pyrroloquinoline quinone (PQQ) improves pulmonary hypertension by regulating mitochondrial and metabolic functions Pulmonary pharmacology & therapeutics, 2022-08-25;76(0):102156. 2022-08-25 [PMID: 36030026] (Rat)
• ASI Salgado, MH Takemoto, CFTC de Souza, DC Salm, D da Rosa, GC Cardoso, DD Ludtke, SFC Soares, JK Ferreira, AR Dutra, YC Szeremeta, G Mazzardo, J Mayra, DDL Sheffer, W Caumo, EB Bittencour, R Schleip, A Latini, F Bobinski, DF Martins Gentle Touch Therapy, Pain Relief and Neuroplasticity at Baseline in Fibromyalgia Syndrome: A Randomized, Multicenter Trial with Six-Month Follow-Up Journal of Clinical Medicine, 2022-08-20;11(16):. 2022-08-20 [PMID: 36013137] (Human)
• L Sansone, A de Iure, M Cristina, M Belli, L Vitiello, F Marcolongo, A Rosellini, L Macera, PG Spezia, C Tomino, S Bonassi, MA Russo, F Maggi, P Russo Nicotine in Combination with SARS-CoV-2 Affects Cells Viability, Inflammatory Response and Ultrastructural Integrity International Journal of Molecular Sciences, 2022-08-22;23(16):. 2022-08-22 [PMID: 36012747] (Human)
• LAJ Feather, V Nadella, E Kastner, Y Perrie, AC Hilton, A Devitt Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems Scientific Reports, 2022-07-20;12(1):12448. 2022-07-20 [PMID: 35859154] (Human)
• SI Johanns, RG Gantin, B Wangala, K Komlan, WA Halatoko, M Banla, P Karabou, AJ Luty, H Schulz-Key, C Köhler, PT Soboslay Onchocerca volvulus-specific antibody and cellular responses in onchocerciasis patients treated annually with ivermectin for 30 years and exposed to parasite transmission in central Togo PloS Neglected Tropical Diseases, 2022-05-03;16(5):e0010340. 2022-05-03 [PMID: 35503786] (Human)
• H Janbazacya, J van Bergen, S Varasteh, J Garssen, G Folkerts, S Braber Repeated exposure of bronchial epithelial cells to particular matter increases allergen-induced cytokine release and permeability Cytokine, 2022-04-08;154(0):155878. 2022-04-08 [PMID: 35405483] (Human)
• LM de-Oliveir, VE Fiestas So, M de Lourdes, C Fernandes-, PH Damasco, MAMT de Siqueir, HG Dias, A Pauvolid-C, PV Damasco, EL de Azeredo Comparative Analysis of Circulating Levels of SARS-CoV-2 Antibodies and Inflammatory Mediators in Healthcare Workers and COVID-19 Patients Viruses, 2022-02-23;14(3):. 2022-02-23 [PMID: 35336861] (Human)
• G Szylar, R Wysoczansk, H Marshall, DJB Marks, R José, ME Ehrenstein, JS Brown A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site Scientific Reports, 2022-03-07;12(1):3990. 2022-03-07 [PMID: 35256717] (Human)
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Bioinformatics

• Gene Symbol: IL10