Human IFN-gamma DuoSet ELISA, 15 Plate

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Summary
Product Discontinued
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    • Catalog Number
      DY285
    • Availability
      Product Discontinued

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Human IFN-gamma DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
IFNG

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY285.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IFN-gamma DuoSet ELISA, 15 Plate

  • IFG
  • IFI
  • IFNG
  • IFNgamma
  • IFN-gamma
  • Immune interferon
  • interferon gamma
  • interferon, gamma

Background

IFN-gamma (Interferon-gamma) is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, upregulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects. In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits.

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Applications: ELISA

Publications for IFN-gamma (DY285)(186)

We have publications tested in 4 confirmed species: Human, Mouse, Primate - Presbytis entellus (Indian langur), Transgenic Mouse.


Filter By Application
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Filter By Species
Human
(180)
Mouse
(3)
Primate - Presbytis entellus (Indian langur)
(1)
Transgenic Mouse
(1)
All Species
Showing Publications 1 - 10 of 186. Show All 186 Publications.
Publications using DY285 Applications Species
Ghaffarpour, S;Ghazanfari, T;Ardestani, SK;Naghizadeh, MM;Vaez Mahdavi, MR;Salehi, M;Majd, AMM;Rashidi, A;Chenary, MR;Mostafazadeh, A;Rezaei, A;Khodadadi, A;Iranparast, S;Khazaei, HA; Cytokine profiles dynamics in COVID-19 patients: a longitudinal analysis of disease severity and outcomes Scientific reports 2025-04-23 [PMID: 40269030] (Human) Human
Ishii, K;Davies, JS;Sinkoe, AL;Nguyen, KA;Norberg, SM;McIntosh, CP;Kadakia, T;Serna, C;Rae, Z;Kelly, MC;Hinrichs, CS; Multi-tiered approach to detect autoimmune cross-reactivity of therapeutic T cell receptors Science advances 2023-07-28 [PMID: 37494434] (Human) Human
D Rasoulouni, N Santana-Ma, A Gutwillig, L Farhat-You, L Tal, S Amar, M Milyavsky, SSNA Muddineni, N Solomon, H Shpilt, S Dotan, N Pilpel, C Waskow, M Feinmesser, P Rider, Y Carmi T Cells Expressing a Modified FcgammaRI Exert Antibody-Dependent Cytotoxicity and Overcome the Limitations of CAR T-cell Therapy against Solid Tumors Cancer Immunology Research, 2023-06-02;0(0):OF1-OF18. 2023-06-02 [PMID: 37070661] (Human) Human
RM Soliman, K Nishioka, T Daidoji, O Noyori, T Nakaya Chimeric Newcastle Disease Virus Vectors Expressing Human IFN-gamma Mediate Target Immune Responses and Enable Multifaceted Treatments Biomedicines, 2023-02-04;11(2):. 2023-02-04 [PMID: 36830991] (Human) Human
RL Schmitz, KE Tweed, P Rehani, K Samimi, J Riendeau, I Jones, EM Maly, EC Guzman, MH Forsberg, A Shahi, CM Capitini, AJ Walsh, MC Skala Autofluorescence lifetime imaging classifies human lymphocyte activation and subtype bioRxiv : the preprint server for biology, 2023-01-23;0(0):. 2023-01-23 [PMID: 36747690] (Human) Human
H Asashima, S Mohanty, M Comi, WE Ruff, KB Hoehn, P Wong, J Klein, C Lucas, I Cohen, S Coffey, N Lele, L Greta, K Raddassi, O Chaudhary, A Unterman, B Emu, SH Kleinstein, RR Montgomery, A Iwasaki, CS Dela Cruz, N Kaminski, AC Shaw, DA Hafler, TS Sumida PD-1highCXCR5-CD4+ peripheral helper T�cells promote CXCR3+ plasmablasts in human acute viral infection Cell Reports, 2023-01-02;0(0):111895. 2023-01-02 [PMID: 36596303] (Human) Human
AJ Eakin, T Ahmed, CM McGeough, S Drain, HD Alexander, GD Wright, PV Gardiner, D Small, AJ Bjourson, DS Gibson CD169+ Monocyte and Regulatory T Cell Subsets Are Associated with Disease Activity in Rheumatoid Arthritis Journal of personalized medicine, 2022-11-09;12(11):. 2022-11-09 [PMID: 36579595] (Human) Human
J Qiao, J Liu, JC Jacobson, RA Clark, S Lee, L Liu, Z An, N Zhang, DH Chung Anti-GRP-R monoclonal antibody antitumor therapy against neuroblastoma PLoS ONE, 2022-12-16;17(12):e0277956. 2022-12-16 [PMID: 36525420] (Human) Human
LU Teufel, CI van der Ma, V Klück, A Simons, A Hoischen, V Vernimmen, LAB Joosten, RJW Arts Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study Cytokine, 2022-12-05;162(0):156102. 2022-12-05 [PMID: 36476991] (Human) Human
Y Wang, Y Zhao, W Guo, GS Yadav, C Bhaskarla, Z Wang, X Wang, S Li, Y Wang, Y Chen, D Pattarayan, W Xie, S Li, B Lu, US Kammula, M Zhang, D Yang Genome-wide gain-of-function screening characterized lncRNA regulators for tumor immune response Science Advances, 2022-12-07;8(49):eadd0005. 2022-12-07 [PMID: 36475797] (Human) Human
Show All 186 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for IFN-gamma (DY285). (Showing 1 - 2 of 2 FAQs).

  1. Is Recombinant Human IFN-gamma Protein - Clinical grade or preclinical ?
    • We are research use only.
  2. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Additional IFN-gamma Products

Blogs on IFN-gamma.

Tired T cells: Hypoxia Drives T cell Exhaustion in the Tumor Microenvironment
By Hunter MartinezThe paradigm shifting view of the immune system being leveraged to target cancer has led to numerous therapeutic breakthroughs. One major cell group responsible for this revelation is a T cell. ...  Read full blog post.

Early T cell response is associated with mild COVID-19 and rapid SARS-CoV-2 clearance
Jamshed Arslan, Pharm D, PhD SARS-CoV-2 induces both humoral and cellular immunity. A vaccine or natural infection invokes SARS-CoV-2-specific humoral components (antibodies from activated B cells) and cellular resp...  Read full blog post.


  Read full blog post.

Success of combined IL-10 and IL-12 therapy in colon cancer depends on IFN-gamma and gut barrier integrity
By Jamshed Arslan, Pharm. D., PhD. Colon cancer is responsible for over 600,000 deaths per year worldwide. Colon cancer can be classified into two categories: mismatch repair (MMR)-deficient and MMR-proficient cancers...  Read full blog post.

You complete me: Natural killer cells need TGF-beta inhibition to effectively combat cancers
By Jamshed Arslan Pharm.D. Natural killer (NK) cells are lymphocytes of the innate immune system that were first discovered for their “natural” ability to kill cancer cells. To use NK cells as anti-cancer therapy, t...  Read full blog post.

iNOS: The Nitric Oxide Boss
Nitric oxide (NO) is an inorganic, gaseous, and reactive free radical that acts as a biologic mediator in processes such as neurotransmission, vasorelaxation, and cytotoxicity. In addition, it has antimicrobial and anti-tumoral activities. NO producti...  Read full blog post.

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Bioinformatics

Gene Symbol IFNG