Human GDF-11/BMP-11 DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human GDF-11/BMP-11 DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: GDF11

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human GDF-11/BMP-11 DuoSet ELISA, 5 Plate

• BMP11
• BMP-11
• BMP-11BMP11Bone morphogenetic protein 11
• GDF11
• GDF-11
• growth differentiation factor 11
• growth/differentiation factor 11

Background

Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.

Publications for GDF-11/BMP-11 (DY1958-05)(5)

Publications using DY1958-05

• Marohl, T;Atkins, KA;Wang, L;Janes, KA; PCSK5M452I is a recessive hypomorph exclusive to MCF10DCIS.com cells bioRxiv : the preprint server for biology 2025-03-07 [PMID: 40093128] (Human)
• YJ Kim, DH Seo, SH Lee, SH Lee, GH An, HJ Ahn, D Kwon, KW Seo, KS Kang Conditioned media from human umbilical cord blood-derived mesenchymal stem cells stimulate rejuvenation function in human skin Biochem Biophys Rep, 2018-10-25;16(0):96-102. 2018-10-25 [PMID: 30417126] (Human)
• LV Barrios-Si, M Parnell, ZB Shinwari, GA Chaudhary, T Xenofontos, A van Bekhov, S McArthur, BT Elliott Activin subfamily peptides predict chronological age in humans Physiol Rep, 2018-09-01;6(17):e13823. 2018-09-01 [PMID: 30178598] (Human)
• BT Elliott, P Herbert, N Sculthorpe, FM Grace, D Stratton, LD Hayes Lifelong exercise, but not short-term high-intensity interval training, increases GDF11, a marker of successful aging: a�preliminary investigation Physiol Rep, 2017-07-11;5(13):. 2017-07-11 [PMID: 28701523] (Human)
• JL Chen, KL Walton, A Hagg, TD Colgan, K Johnson, H Qian, P Gregorevic, CA Harrison Specific targeting of TGF-? family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease Proc. Natl. Acad. Sci. U.S.A., 2017-06-12;0(0):. 2017-06-12 [PMID: 28607086] (Mouse)

FAQs for GDF-11/BMP-11 (DY1958-05). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: GDF11