Human Chymase/CMA1 DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Chymase/CMA1 DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Chymase/CMA1 DuoSet ELISA, 5 Plate

• Alpha-chymase
• chymase 1 preproprotein transcript E
• chymase 1 preproprotein transcript I
• chymase 1, mast cell
• Chymase
• chymase, heart
• chymase, mast cell
• CMA1
• CYH
• CYM
• EC 3.4.21
• EC 3.4.21.39
• Mast cell protease I
• MCP3P
• Mcpt5
• MCT1
• MGC119890
• MGC119891

Background

Chymases are a group of chymotrypsin-like serine proteases secreted by mast cells. They are synthesized as inactive precursors containing a 2-residue propeptide, which needs to be removed by dipeptidyl peptidase I/cathepsin C for enzymatic activity. Human chymase encoded by the CMA1 gene is known to be involved in hypertension and heart failure through its ability to convert angiotensin I (Ang I) to angiotensin II (Ang II). In addition, it is also important in physiological and pathological conditions including inflammation, fibrosis and processing of cytokines.

Publications for Chymase/CMA1/Mast Cell Chymase (DY4099-05)(2)

Publications using DY4099-05

• Liu, J;Liu, S;Zeng, L;Tsilioni, I; Amyloid Beta Peptides Lead to Mast Cell Activation in a Novel 3D Hydrogel Model International journal of molecular sciences 2023-07-26 [PMID: 37569378] (Human)
• Tsilioni, I;Theoharides, TC; Recombinant SARS-CoV-2 Spike Protein Stimulates Secretion of Chymase, Tryptase, and IL-1? from Human Mast Cells, Augmented by IL-33 International journal of molecular sciences 2023-05-30 [PMID: 37298438] (Human)

FAQs for Chymase/CMA1/Mast Cell Chymase (DY4099-05). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.