Human CCL19/MIP-3 beta DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human CCL19/MIP-3 beta DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CCL19

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CCL19/MIP-3 beta DuoSet ELISA, 15 Plate

• beta chemokine exodus-3
• Beta-chemokine exodus-3
• CC chemokine ligand 19
• C-C motif chemokine 19
• CCL19
• chemokine (C-C motif) ligand 19
• CKb11
• EBI1-ligand chemokine
• ELC
• ELCMIP-3-beta
• Epstein-Barr virus-induced molecule 1 ligand chemokine
• exodus-3
• Macrophage inflammatory protein 3 beta
• macrophage inflammatory protein 3-beta
• MGC34433
• MIP3 beta
• MIP-3 beta
• MIP-3b
• MIP3BCK beta-11
• SCYA19EBI1 ligand chemokine
• small inducible cytokine subfamily A (Cys-Cys), member 19
• Small-inducible cytokine A19

Background

Macrophage inflammatory protein 3 beta (MIP-3 beta), also known as ELC (EBI1-ligand chemokine) and exodus-3, is constitutively expressed in various lymphoid tissues, including thymus, lymph nodes, appendix and spleen. It is distantly related to other CC chemokines (20-30% amino acid sequence identity).

Publications for CCL19/MIP-3 beta (DY361)(21)

Publications using DY361

• W Alturaiki, H Alkadi, S Alamri, ME Awadalla, A Alfaez, A Mubarak, MA Alanazi, FQ Alenzi, BF Flanagan, B Alosaimi Association between the expression of Toll-like receptors, cytokines, and homeostatic chemokines in SARS-CoV-2 infection and COVID-19 severity Heliyon, 2022-12-24;0(0):e12653. 2022-12-24 [PMID: 36589720] (Human)
• X Guo, T Xu, J Zheng, X Cui, M Li, K Wang, M Su, H Zhang, K Zheng, C Sun, S Song, H Liu Accumulation of synovial fluid CD19+CD24hiCD27+ B cells was associated with bone destruction in rheumatoid arthritis Sci Rep, 2020-09-01;10(1):14386. 2020-09-01 [PMID: 32873834] (Human)
• JS Hähnlein, TH Ramwadhdoe, JF Semmelink, IY Choi, FH Berger, M Maas, DM Gerlag, PP Tak, TBH Geijtenbee, LGM van Baarse Distinctive expression of T cell guiding molecules in human autoimmune lymph node stromal cells upon TLR3 triggering Sci Rep, 2018-01-29;8(1):1736. 2018-01-29 [PMID: 29379035] (Human)
• A Forestier, T Guerrier, M Jouvray, J Giovannell, G Lefèvre, V Sobanski, C Hauspie, E Hachulla, PY Hatron, H Zephir, P Vermersch, M Labalette, D Launay, S Dubucquoi Altered B lymphocyte homeostasis and functions in systemic sclerosis Autoimmun Rev, 2018-01-16;0(0):. 2018-01-16 [PMID: 29343447] (ELISA Capture, Human)
• J Lee, C Park, HJ Kim, YD Lee, ZH Lee, YW Song, HH Kim Stimulation of osteoclast migration and bone resorption by C-C chemokine ligands 19 and 21 Exp. Mol. Med., 2017-07-21;49(7):e358. 2017-07-21 [PMID: 28729639] (Human)
• P Severino, DT Palomino, H Alvarenga, CB Almeida, DC Pasqualim, A Cury, PR Salvalaggi, AL De Vasconc, MC Andrade, T Aloia, S Bromberg, LV Rizzo, FA Rocha, LC Marti Human Lymph Node-Derived Fibroblastic and Double-Negative Reticular Cells Alter Their Chemokines and Cytokines Expression Profile Following Inflammatory Stimuli Front Immunol, 2017-02-14;8(0):141. 2017-02-14 [PMID: 28261205] (Human)
• Kudo-Saito C, Yura M, Yamamoto R, Kawakami Y Induction of immunoregulatory CD271+ cells by metastatic tumor cells that express human endogenous retrovirus H. Cancer Res, 2014-03-01;74(5):1361-70. 2014-03-01 [PMID: 24590808] (Human)
• Astrup E, Janardhanan J, Otterdal K, Ueland T, Prakash J, Lekva T, Strand O, Abraham O, Thomas K, Damas J, Mathews P, Mathai D, Aukrust P, Varghese G Cytokine network in scrub typhus: high levels of interleukin-8 are associated with disease severity and mortality. PLoS Negl Trop Dis, 2014-02-06;8(2):e2648. 2014-02-06 [PMID: 24516677] (Human)
• Edwards , Keith R, Goyal , Jaya, Plavina , Tatiana, Czerkowicz , Julie, Goelz , Susan, Ranger , Ann, Cadavid , Diego, Browning , Jeffrey Feasibility of the use of combinatorial chemokine arrays to study blood and CSF in multiple sclerosis. PLoS ONE, 2013-11-20;8(11):e81007. 2013-11-20 [PMID: 24278364] (Human)
• Vujanovic , Lazar, Ballard , Wenners, Thorne , Stephen, Vujanovic , Nikola L, Butterfield , Lisa H Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10. Oncoimmunology, 2012-07-01;1(4):448-457. 2012-07-01 [PMID: 22754763] (Human)
• Quesnel C, Piednoir P, Gelly J, Nardelli L, Garnier M, Lecon V, Lasocki S, Bouadma L, Philip I, Elbim C, Mentre F, Soler P, Crestani B, Dehoux M Alveolar fibrocyte percentage is an independent predictor of poor outcome in patients with acute lung injury. Crit. Care Med., 2012-01-01;40(1):21-8. 2012-01-01 [PMID: 21926612] (Human)
• Zimmer A, Luce S, Gaignier F, Nony E, Naveau M, Biola-Vidamment A, Pallardy M, Van Overtvelt L, Mascarell L, Moingeon P Identification of a New Phenotype of Tolerogenic Human Dendritic Cells Induced by Fungal Proteases from Aspergillus oryzae. J. Immunol., 2011-03-02;186(7):3966-76. 2011-03-02 [PMID: 21368225] (Human)
• Damas JK, Landro L, Fevang B, Heggelund L, Tjonnfjord GE, Floisand Y, Halvorsen B, Froland SS, Aukrust P Homeostatic chemokines CCL19 and CCL21 promote inflammation in human immunodeficiency virus-infected patients with ongoing viral replication. Clin. Exp. Immunol., 2009-09-01;157(3):400-7. 2009-09-01 [PMID: 19664149] (Human)
• Krumbholz M, Theil D, Steinmeyer F, Cepok S, Hemmer B, Hofbauer M, Farina C, Derfuss T, Junker A, Arzberger T, Sinicina I, Hartle C, Newcombe J, Hohlfeld R, Meinl E CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions. J. Neuroimmunol., 2007-09-06;190(1):72-9. 2007-09-06 [PMID: 17825430] (Human)
• Shields JD, Fleury ME, Yong C, Tomei AA, Randolph GJ, Swartz MA Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell, 2007-06-01;11(6):526-38. 2007-06-01 [PMID: 17560334] (Human)
• Pietila TE, Veckman V, Lehtonen A, Lin R, Hiscott J, Julkunen I Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells. J. Immunol., 2007-01-01;178(1):253-61. 2007-01-01 [PMID: 17182562] (Human)
• Walker J, Tough DF Modification of TLR-induced activation of human dendritic cells by type I IFN: synergistic interaction with TLR4 but not TLR3 agonists. Eur. J. Immunol., 2006-07-01;36(7):1827-36. 2006-07-01 [PMID: 16783851] (Human)
• Haukeland JW, Damas JK, Konopski Z, Loberg EM, Haaland T, Goverud I, Torjesen PA, Birkeland K, Bjoro K, Aukrust P Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2. J. Hepatol., 2006-03-20;44(6):1167-74. 2006-03-20 [PMID: 16618517] (Human)
• Daikoku N, Kitaya K, Nakayama T, Fushiki S, Honjo H Expression of macrophage inflammatory protein-3beta in human endometrium throughout the menstrual cycle. Fertil. Steril., 2004-03-01;81(0):876-81. 2004-03-01 [PMID: 15019823] (Human)
• Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS. J. Leukoc. Biol., 2003-05-01;73(5):584-90. 2003-05-01 [PMID: 12714572] (Human)
• Gibejova A, Mrazek F, Subrtova D, Sekerova V, Szotkowska J, Kolek V, du Bois RM, Petrek M Expression of macrophage inflammatory protein-3 beta/CCL19 in pulmonary sarcoidosis. Am. J. Respir. Crit. Care Med., 2003-03-05;167(12):1695-703. 2003-03-05 [PMID: 12626344] (Human)

FAQs for CCL19/MIP-3 beta (DY361). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: CCL19