Human C-Reactive Protein/CRP Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human C-Reactive Protein/CRP Quantikine ELISA Kit Summary

Background
The Quantikine Human C-Reactive Protein/CRP Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human CRP in cell culture supernates, serum, and plasma. It contains recombinant human CRP and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human CRP showed linear curves that were parallel to the standard curves obtained using the Quan...tikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human CRP.
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Additional Information
Quantikine Quickit version available - results in 90 minutes (QK1707).
Specificity
Natural and recombinant human CRP.
Source
N/A
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
DCRP00B in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human C-Reactive Protein/CRP Quantikine ELISA Kit

  • C-Reactive Protein
  • C-reactive protein, pentraxin-related
  • CRP
  • MGC88244
  • pentraxin 1
  • PTX1MGC149895

Background

C-Reactive Protein (CRP), also known as Pentraxin 1, is a secreted pentameric protein that functions as a sensor and activator for the innate immune response. In humans, it is a major acute-phase protein; its circulating concentration is dramatically elevated at the onset of inflammation. In mice, however, serum CRP levels increase only slightly during inflammation, and the analogous acute phase role is filled by Pentraxin 2. CRP binds, opsonizes, and induces the phagocytosis of bacteria and apoptotic cells. It regulates activation of the classical complement pathway by binding several proteins in the complement cascade as well as Fc gamma RI, Fc gamma RIIA, and Fc gamma RIIB on macrophages and dendritic cells. It also promotes dendritic cell maturation and humoral immunity. In cardiovascular disease, CRP binds to oxidized LDL, exacerbates tissue damage in myocardial infarction, and inhibits the repair of injured vascular endothelium.

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Publications for C-Reactive Protein/CRP (DCRP00B)(157)

We have publications tested in 4 confirmed species: Human, Mouse, Transgenic Mouse,  Human.

We have publications tested in 1 application: ELISA Capture.


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ELISA Capture
(1)
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Human
(154)
Mouse
(1)
Transgenic Mouse
(1)
 Human
(1)
All Species
Showing Publications 1 - 10 of 157. Show All 157 Publications.
Publications using DCRP00B Applications Species
Yañuk, DB;Cellucci, AS;Marta, RF;Discianni Lupi, AD;De Luca, G;Glembotsky, AC;Rios, MAC;Moiraghi, B;Sackmann, F;Guerrieri, VC;Heller, PG;Goette, NP;Lev, PR; Inflammatory mediators differentially regulate megakaryopoiesis and thrombopoiesis in myelofibrosis and essential thrombocythemia Scientific reports 2025-12-12 [PMID: 41388056] (Human) Human
Bhowmick, S;Devadiga, P;Yadav, S;Mohite, N;Gurav, P;Pandey, T;Padwal, V;Neman, N;Suryawanshi, A;Musale, S;Singh, AK;Bhagat, S;Kaginkar, S;Palav, H;Birje, S;Kerkar, S;Idicula-Thomas, S;Nagar, V;Patil, P;Agrawal, S;Gaikwad, S;Shastri, J;Mukherjee, N;Munne, K;Bhor, VM;Madan, T;Patel, V; Protective Immune Signatures Associated with Latent TB Infection in PLHIV-Insights from an Integrative Prospective Immune Monitoring Study Cells 2025-10-17 [PMID: 41148837] (Human) Human
Bade, N;Hellman, DA;Matye, DJ;Jiang, S;Tryggestad, JB;Yu, Z;Short, KR;Palle, SK; A Comparison of Novel Serum Markers of Liver Health in Adolescents With Metabolic Dysfunction-Associated Steatotic Liver Disease Journal of cellular and molecular medicine 2025-08-01 [PMID: 40874510] (Human) Human
Meng, Y;Lu, J;Shi, C;Zhu, H;Zhang, J; Serum moesin is associated with cognitive impairment and glucose fluctuations in patients with type 2 diabetes Diabetology & metabolic syndrome 2025-07-29 [PMID: 40734173] (Human) Human
Jackson, DM;Castanon-Cervantes, O; Impaired Responses to In Vitro Lipopolysaccharide-Induced Stimulation After Long-Term, Rotating Shift Work International journal of environmental research and public health 2025-05-17 [PMID: 40427905] (Human) Human
Ezzati, A;Tamargo, JA;Golberg, L;Haub, MD;Anton, SD; The Effects of Time-Restricted Eating on Inflammation and Oxidative Stress in Overweight Older Adults: A Pilot Study Nutrients 2025-01-17 [PMID: 39861451] (Human) Human
Noori, AS;Rajabi, P;Sargolzaei, J;Alaghmand, A; Correlation of biochemical markers and inflammatory cytokines in autism spectrum disorder (ASD) BMC pediatrics 2024-11-01 [PMID: 39487445] (Human) Human
O'Hora, KP;Amir, CM;Chiem, E;Schleifer, CH;Grigoryan, V;Kushan-Wells, L;Chiang, JJ;Cole, S;Irwin, MR;Bearden, CE; Differential inflammatory profiles in carriers of reciprocal 22q11.2 copy number variants Psychoneuroendocrinology 2024-07-20 [PMID: 39116521] (Human) Human
Dupnik, K;Rivera, VR;Dorvil, N;Duffus, Y;Akbarnejad, H;Gao, Y;Liu, J;Apollon, A;Dumont, E;Riviere, C;Severe, P;Lavoile, K;Duran Mendicuti, MA;Pierre, S;Rouzier, V;Walsh, KF;Byrne, AL;Joseph, P;Cremieux, PY;Pape, JW;Koenig, SP; Potential Utility of C-reactive Protein for Tuberculosis Risk Stratification Among Patients With Non-Meningitic Symptoms at HIV Diagnosis in Low- and Middle-income Countries Open forum infectious diseases 2024-07-01 [PMID: 39022393] (Human) Human
Atieh, O;Durieux, JC;Baissary, J;Mouchati, C;Labbato, D;Thomas, A;Merheb, A;Ailstock, K;Funderburg, N;McComsey, GA; The Long-Term Effect of COVID-19 Infection on Body Composition Nutrients 2024-04-30 [PMID: 38732609] (Human) Human
Show All 157 Publications.

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Product General Protocols

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FAQs for C-Reactive Protein/CRP (DCRP00B). (Showing 1 - 1 of 1 FAQs).

  1. What is the difference between the Quantikine and Duoset ELISA kits?
    • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

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