Human C-Reactive Protein/CRP Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human C-Reactive Protein/CRP Quantikine ELISA Kit Summary

Background
The Quantikine Human C-Reactive Protein/CRP Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human CRP in cell culture supernates, serum, and plasma. It contains recombinant human CRP and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human CRP showed linear curves that were parallel to the standard curves obtained using the Quan...tikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human CRP.
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Specificity
Natural and recombinant human CRP.
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
DCRP00B in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human C-Reactive Protein/CRP Quantikine ELISA Kit

  • C-Reactive Protein
  • C-reactive protein, pentraxin-related
  • CRP
  • MGC88244
  • pentraxin 1
  • PTX1MGC149895

Background

C-Reactive Protein (CRP), also known as Pentraxin 1, is a secreted pentameric protein that functions as a sensor and activator for the innate immune response. In humans, it is a major acute-phase protein; its circulating concentration is dramatically elevated at the onset of inflammation. In mice, however, serum CRP levels increase only slightly during inflammation, and the analogous acute phase role is filled by Pentraxin 2. CRP binds, opsonizes, and induces the phagocytosis of bacteria and apoptotic cells. It regulates activation of the classical complement pathway by binding several proteins in the complement cascade as well as Fc gamma RI, Fc gamma RIIA, and Fc gamma RIIB on macrophages and dendritic cells. It also promotes dendritic cell maturation and humoral immunity. In cardiovascular disease, CRP binds to oxidized LDL, exacerbates tissue damage in myocardial infarction, and inhibits the repair of injured vascular endothelium.

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Publications for C-Reactive Protein/CRP (DCRP00B)(139)

We have publications tested in 3 confirmed species: Human, Mouse, Transgenic Mouse.

We have publications tested in 1 application: ELISA Capture.


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ELISA Capture
(1)
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Human
(137)
Mouse
(1)
Transgenic Mouse
(1)
All Species
Showing Publications 1 - 10 of 139. Show All 139 Publications.
Publications using DCRP00B Applications Species
Corley, E;Patlola, SR;Laighneach, A;Corvin, A;McManus, R;Kenyon, M;Kelly, JP;Mckernan, DP;King, S;Hallahan, B;Mcdonald, C;Morris, DW;Donohoe, G; Genetic and inflammatory effects on childhood trauma and cognitive functioning in patients with schizophrenia and healthy participants Brain, behavior, and immunity 2023-09-23 [PMID: 37748567] (Human) Human
Hoogland, A;Small, B;Oswald, L;Bryant, C;Rodriguez, Y;Gonzalez, B;Li, X;Janelsins, M;Bulls, H;James, B;Arboleda, B;Colon-Echevarria, C;Townsend, M;Tworoger, S;Rodriguez, P;Bower, J;Apte, S;Wenham, R;Jim, H; Relationships among Inflammatory Biomarkers and Self-Reported Treatment-Related Symptoms in Patients Treated with Chemotherapy for Gynecologic Cancer: A Controlled Comparison Cancers 2023-01-01 [PMID: 37444517] (Human) Human
Belkin, S;Benthien, J;Axt, PN;Mohr, T;Mortensen, K;Weckmann, M;Drömann, D;Franzen, KF; Impact of Heated Tobacco Products, E-Cigarettes, and Cigarettes on Inflammation and Endothelial Dysfunction International journal of molecular sciences 2023-05-29 [PMID: 37298381] (Human) Human
Al Asmari, AK;Al Shehri, HA;Khan, HA;Al Omani, S;Kadasah, SG;Horaib, GB;Al Buraidi, A;Al Sharif, AA;Mohammed, FS;Abbasmanthiri, R;Osman, NM; Serum Levels of Proinflammatory Biomarkers in Military Recruits with and without Metabolic Syndrome Mediators of inflammation 2023-04-30 [PMID: 37168278] (Human) Human
H Hallihan, P Tsai, N Lv, L Xiao, B Peñalver B, Y Wu, GN Pandey, LM Williams, OA Ajilore, J Ma Affective neural circuits and inflammatory markers linked to depression and anxiety symptoms in patients with comorbid obesity Journal of psychiatric research, 2023-02-03;160(0):9-18. 2023-02-03 [PMID: 36764197] (Human) Human
X Luo, Z Fang, L Lin, H Xu, Q Huang, H Zhang Plasma complement C3 and C3a are increased in major depressive disorder independent of childhood trauma BMC Psychiatry, 2022-11-29;22(1):741. 2022-11-29 [PMID: 36447174] (Human) Human
AH Cincotta, E Cersosimo, M Alatrach, M Ezrokhi, C Agyin, J Adams, R Chilton, C Triplitt, B Chamarthi, N Cominos, RA DeFronzo Bromocriptine-QR Therapy Reduces Sympathetic Tone and Ameliorates a Pro-Oxidative/Pro-Inflammatory Phenotype in Peripheral Blood Mononuclear Cells and Plasma of Type 2 Diabetes Subjects International Journal of Molecular Sciences, 2022-08-09;23(16):. 2022-08-09 [PMID: 36012132] (Human) Human
S Mahgoub, SS Fatahala, AI Sayed, HB Atya, MF El-Shehry, H Afifi, SM Awad, RHA El-Hameed, H Taha Novel hit of DPP-4Is as promising antihyperglycemic agents with dual antioxidant/anti-inflammatory effects for type 2 diabetes with/without COVID-19 Bioorganic chemistry, 2022-08-10;128(0):106092. 2022-08-10 [PMID: 35985159] (Human) Human
H Svensson, S Einarsson, D Olausson, L Kluge, C Bergh, S Edén, M Lönn, A Thurin-Kje Inflammatory and metabolic markers in relation to outcome of in vitro fertilization in a cohort of predominantly overweight and obese women Scientific Reports, 2022-08-03;12(1):13331. 2022-08-03 [PMID: 35922472] (Human) Human
LS Silva-Berm, A Vargas-Vil, CA Sánchez-Va, AC Palacio, AF Buitrago, CO Mendivil Peri-event plasma PCSK9 and hsCRP after an acute myocardial infarction correlate with early deterioration of left ventricular ejection fraction: a cohort study Oncogene, 2022-07-21;21(1):61. 2022-07-21 [PMID: 35864531] (Human) Human
Show All 139 Publications.

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