Human Haptoglobin Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human Haptoglobin Quantikine ELISA Kit Summary

Background
The Quantikine Human Haptoglobin Immunoassay is a 4.5 hour solid phase ELISA designed to measure haptoglobin in serum-free cell culture supernates, serum, plasma, saliva, and urine
Specificity
Natural human haptoglobin
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
HP

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DHAPG0.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Haptoglobin Quantikine ELISA Kit

  • binding peptide
  • BP
  • haptoglobin alpha(1S)-beta
  • haptoglobin alpha(2FS)-beta
  • Haptoglobin
  • haptoglobin, alpha polypeptide
  • haptoglobin, beta polypeptide
  • HP
  • HP-1
  • hp2-alpha
  • HP2ALPHA2
  • HPA1S
  • MGC111141
  • zonulin

Background

Haptoglobin is an acute phase glycoprotein that is an inactive member of the peptidase S1 family of serine proteases. It is secreted by multiple cell types and binds with high affinity to circulating Hemoglobin. Association of Haptoglobin with free Hemoglobin protects tissues from Hemoglobin-mediated oxidative damage and facilitates Hemoglobin clearance. In addition, Haptoglobin has anti-inflammatory properties that are independent of Hemoglobin binding. It inhibits prostaglandin synthesis, scavenges nitric oxide, dampens the inflammatory response to endotoxins, and inhibits T cell proliferation and neutrophil respiratory bursts. Deletion of Haptoglobin in mice facilitates the development of autoimmune inflammation.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Haptoglobin (DHAPG0)(6)

We have publications tested in 1 confirmed species: Human.


Filter By Application
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Filter By Species
Human
(6)
All Species
Showing Publications 1 - 6 of 6.
Publications using DHAPG0 Applications Species
A Olsson, S Gustavsen, IC Hasselbalc, AR Langkilde, F Sellebjerg, AB Oturai, HB Søndergaar Biomarkers of inflammation and epithelial barrier function in multiple sclerosis Mult Scler Relat Disord, 2020;46(0):102520. 2020 [PMID: 32980645] (Human) Human
A Wiedemann, E Foucat, H Hocini, C Lefebvre, BP Hejblum, M Durand, M Krüger, AK Keita, A Ayouba, S Mély, JC Fernandez, A Touré, S Fourati, C Lévy-March, H Raoul, E Delaporte, L Koivogui, R Thiébaut, C Lacabaratz, Y Lévy, Long-lasting severe immune dysfunction in Ebola virus disease survivors Nat Commun, 2020;11(1):3730. 2020 [PMID: 32709840] (Human) Human
NK Sharma, BL Ferreira, AK Tashima, MKC Brunialti, RJS Torquato, A Bafi, M Assuncao, LCP Azevedo, R Salomao Lipid metabolism impairment in patients with sepsis secondary to hospital acquired pneumonia, a proteomic analysis Clin Proteomics, 2019;16(0):29. 2019 [PMID: 31341447] (Human) Human
S Wang, J Wang, R Zhang, A Zhao, X Zheng, D Yan, F Jiang, W Jia, C Hu, W Jia Association between serum haptoglobin and carotid arterial functions: usefulness of a targeted metabolomics approach Cardiovasc Diabetol, 2019;18(1):8. 2019 [PMID: 30634984] (Human) Human
RL Gurung, R Dorajoo, S Liu, Y M, JJ Liu, L Wang, L Guo, X Yu, JJ Liu, SC Lim Genetic markers for urine haptoglobin is associated with decline in renal function in type 2 diabetes in East Asians Sci Rep, 2018;8(1):5109. 2018 [PMID: 29572449] (Human) Human
S Wang, J Wang, R Zhang, T Wang, D Yan, Z He, F Jiang, C Hu, W Jia Mendelian randomization analysis to assess a causal effect of haptoglobin on macroangiopathy in Chinese type 2 diabetes patients Cardiovasc Diabetol, 2018;17(1):14. 2018 [PMID: 29338727] (Human) Human

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Blogs on Haptoglobin.

Lipopolysaccharide from gut microbiome localizes in human atherosclerotic plaques and promotes TLR4-mediated oxidative stress
By Jamshed Arslan, Pharm. D., PhD. Atherosclerosis is a chronic inflammatory condition in which plaques of fats and other substances slowly buildup on the inner walls of arteries to restrict blood flow. In atheroscle...  Read full blog post.

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Bioinformatics

Gene Symbol HP