Human C-Reactive Protein/CRP Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Catalog# & Conjugate Size Price

Human C-Reactive Protein/CRP Quantikine ELISA Kit Summary

Background
The Quantikine Human CRP Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human CRP in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human CRP and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human CRP showed linear curves that were parallel to the standard curves obtained using the Quantikin...e kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human CRP.
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Specificity
Natural and recombinant human CRP
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
CRP

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
DCRP00 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human C-Reactive Protein/CRP Quantikine ELISA Kit

  • C-Reactive Protein
  • C-reactive protein, pentraxin-related
  • CRP
  • MGC88244
  • pentraxin 1
  • PTX1MGC149895

Background

C-Reactive Protein (CRP), also known as Pentraxin 1, is a secreted pentameric protein that functions as a sensor and activator for the innate immune response. In humans, it is a major acute-phase protein; its circulating concentration is dramatically elevated at the onset of inflammation. In mice, however, serum CRP levels increase only slightly during inflammation, and the analogous acute phase role is filled by Pentraxin 2. CRP binds, opsonizes, and induces the phagocytosis of bacteria and apoptotic cells. It regulates activation of the classical complement pathway by binding several proteins in the complement cascade as well as Fc gamma RI, Fc gamma RIIA, and Fc gamma RIIB on macrophages and dendritic cells. It also promotes dendritic cell maturation and humoral immunity. In cardiovascular disease, CRP binds to oxidized LDL, exacerbates tissue damage in myocardial infarction, and inhibits the repair of injured vascular endothelium.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for C-Reactive Protein/CRP (DCRP00)(81)

We have publications tested in 2 confirmed species: Human, Transgenic Mouse.

We have publications tested in 1 application: ELISA Capture.


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ELISA Capture
(1)
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Human
(79)
Transgenic Mouse
(1)
All Species
Showing Publications 1 - 10 of 81. Show All 81 Publications.
Publications using DCRP00 Applications Species
S Guglielmet, S Bernardi, C Del Bo', A Cherubini, M Porrini, G Gargari, N Hidalgo-Li, R Gonzalez-D, G Peron, R Zamora-Ros, MS Winterbone, B Kirkup, PA Kroon, C Andres-Lac, P Riso Effect of a polyphenol-rich dietary pattern on intestinal permeability and gut and blood microbiomics in older subjects: study protocol of the MaPLE randomised controlled trial BMC Geriatr, 2020;20(1):77. 2020 [PMID: 32102662] (Human) Human
I Elisia, V Lam, B Cho, M Hay, MY Li, J Kapeluto, T Elliott, D Harris, L Bu, W Jia, H Leung, W Mohn, G Krystal Exploratory examination of inflammation state, immune response and blood cell composition in a human obese cohort to identify potential markers predicting cancer risk PLoS ONE, 2020;15(2):e0228633. 2020 [PMID: 32027700] (Human) Human
JF Camargo, S Pallikkuth, I Moroz, Y Natori, ML Alcaide, A Rodriguez, G Guerra, GW Burke, S Pahwa Pretransplant Levels of C-Reactive Protein,�Soluble TNF Receptor-1, and�CD38+HLADR+ CD8 T Cells Predict Risk of Allograft Rejection in HIV+ Kidney Transplant Recipients Kidney Int Rep, 2019;4(12):1705-1716. 2019 [PMID: 31844807] (Human) Human
A Picca, RT Mankowski, G Kamenov, SD Anton, TM Manini, TW Buford, SK Saini, R Calvani, F Landi, R Bernabei, E Marzetti, C Leeuwenbur Advanced Age Is Associated with Iron Dyshomeostasis and Mitochondrial DNA Damage in Human Skeletal Muscle Cells, 2019;8(12):. 2019 [PMID: 31783583] (Human) Human
M Sotos-Prie, C Christophi, A Black, JD Furtado, Y Song, P Magiatis, A Papakonsta, E Melliou, S Moffatt, SN Kales Assessing Validity of Self-Reported Dietary Intake within a Mediterranean Diet Cluster Randomized Controlled Trial among US Firefighters Nutrients, 2019;11(9):. 2019 [PMID: 31546768] (Human) Human
TJ Wade, DD O'Leary, KS Dempster, AJ MacNeil, DS Molnar, J McGrath, J Cairney Adverse childhood experiences (ACEs) and cardiovascular development from childhood to early adulthood: study protocol of the Niagara Longitudinal Heart Study BMJ Open, 2019;9(7):e030339. 2019 [PMID: 31315878] (Human) Human
TH Chin, CP Lin, SD Chang, HS Wang, HY Huang, YK Soong, HM Wu, PH Chu Application of non-invasive detection of peripheral vascular dysfunction in ovarian hyperstimulation syndrome (OHSS): A pilot study of clinical relevance Taiwan J Obstet Gynecol, 2019;58(3):354-358. 2019 [PMID: 31122524] (Human) Human
H Yao, Y Mizoguchi, A Monji, Y Yakushiji, Y Takashima, A Uchino, T Yuzuriha, M Hashimoto Low-Grade Inflammation Is Associated with Apathy Indirectly via Deep White Matter Lesions in Community-Dwelling Older Adults: The Sefuri Study Int J Mol Sci, 2019;20(8):. 2019 [PMID: 30999680] (Human) Human
AK Ziegler, SM Jensen, P Schjerling, AL Mackey, JL Andersen, M Kjaer The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation Exp. Gerontol., 2019;121(0):19-32. 2019 [PMID: 30905721] (Human) Human
GM Turner-McG, MD Wirth, N Shivappa, CG Dunn, A Crimarco, TG Hurley, DS West, JR Hussey, JR Hébert Impact of a 12-month Inflammation Management Intervention on the Dietary Inflammatory Index, inflammation, and lipids Clin Nutr ESPEN, 2019;30(0):42-51. 2019 [PMID: 30904228] (Human) Human
Show All 81 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for C-Reactive Protein/CRP (DCRP00). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DCRP00
HRP DCRP00
HRP DCRP00

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Bioinformatics

Gene Symbol CRP