Human Angiopoietin-1 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Angiopoietin-1 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: ANGPT1

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Angiopoietin-1 DuoSet ELISA, 15 Plate

• AGP1
• AGPT
• Ang1
• ANG-1
• angiopoietin 1
• Angiopoietin-1
• ANGPT1
• KIAA0003

Background

Angiopoietins, Ang-1, Ang-2, and Ang-3 (mouse)/Ang-4 (human), are natural agonists or antagonists of the Tie-2 receptor tyrosine kinase and are important modulators of angiogenesis. Two domains characterize the angiopoietin family of proteins: an N-terminal coiled-coil domain that mediates homo-oligomerization, and a C-terminal fibrinogen-like domain that binds Tie-2.

Publications for Angiopoietin-1 (DY923)(41)

Publications using DY923

• Mayhew, JA;Witten, AJ;Bond, CA;Opoka, RO;Bangirana, P;Conroy, AL;Hernandez-Alvarado, N;Schleiss, MR;John, CC; Cytomegalovirus reactivation and acute and chronic complications in children with cerebral malaria: a prospective cohort study Malaria journal 2025-02-17 [PMID: 39962580] (Human)
• López-Guzmán, C;García, AM;Marín, P;Vásquez, AM; Assessment of the Integrity and Function of Human Term Placental Explants in Short-Term Culture Methods and protocols 2024-02-15 [PMID: 38392690] (Human)
• Agyekum, JA;Yeboah, K; Peripheral sensory neuropathy is associated with circulating angiopoietins in type 2 diabetes patients in Ghana Journal of clinical & translational endocrinology 2023-12-01 [PMID: 37822668] (Human)
• S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis Journal of ovarian research, 2022-07-26;15(1):87. 2022-07-26 [PMID: 35883110] (Human)
• CE Lekpor, F Botchway, KA Kusi, AA Adjei, MD Wilson, JK Stiles, NO Wilson Angiogenic and angiostatic factors present in the saliva of malaria patients Malaria Journal, 2022-07-14;21(1):220. 2022-07-14 [PMID: 35836234] (Human)
• J Kaur, K Kamboj, AK Yadav, P Kaur, V Kumar, V Jha Cholecalciferol supplementation and angiogenic markers in chronic kidney disease PLoS ONE, 2022-06-03;17(6):e0268946. 2022-06-03 [PMID: 35657784] (Human)
• M Reijrink, J van Ark, CPH Lexis, LM Visser, ME Lodewijk, ICC van der Ho, CJ Zeebregts, H van Goor, SCA de Jager, G Pasterkamp, BHR Wolffenbut, JL Hillebrand Increased frequency of proangiogenic tunica intima endothelial kinase 2 (Tie2) expressing monocytes in individuals with type 2 diabetes mellitus Cardiovascular Diabetology, 2022-05-12;21(1):72. 2022-05-12 [PMID: 35549955] (Human)
• J Ohmes, MD Mikkelsen, TT Nguyen, VHN Tran, S Meier, MS Nielsen, M Ding, A Seekamp, AS Meyer, S Fuchs Depolymerization of fucoidan with endo-fucoidanase changes bioactivity in processes relevant for bone regeneration Carbohydrate polymers, 2022-02-24;286(0):119286. 2022-02-24 [PMID: 35337530] (Human)
• V Tran, AM Weckman, VM Crowley, LS Cahill, K Zhong, A Cabrera, RE Elphinston, V Pearce, M Madanitsa, L Kalilani-P, V Mwapasa, C Khairallah, AL Conroy, FO Ter Kuile, JG Sled, KC Kain The Angiopoietin-Tie2 axis contributes to placental vascular disruption and adverse birth outcomes in malaria in pregnancy EBioMedicine, 2021-11-07;73(0):103683. 2021-11-07 [PMID: 34758414] (Mouse)
• Qimei Gong, Junyu Zeng, Xufang Zhang, Yihua Huang, Chanchan Chen, Jingjing Quan et al. Effect of erythropoietin on angiogenic potential of dental pulp cells Experimental and Therapeutic Medicine 2021-07-28 [PMID: 34447472] (Human)
• E Charles, BL Dumont, S Bonneau, PE Neagoe, L Villeneuve, A Räkel, M White, MG Sirois Angiopoietin 1 release from human neutrophils is independent from neutrophil extracellular traps (NETs) BMC immunology, 2021-08-03;22(1):51. 2021-08-03 [PMID: 34344299] (Human)
• R Urbanavi?i, R Zabitait?, A Kriš?iukai, VP Deltuva, D Skiriut? Serum protein triplet TGF-&beta1, TIMP-1, and YKL-40 serve as diagnostic and prognostic profile for astrocytoma Scientific Reports, 2021-06-23;11(1):13100. 2021-06-23 [PMID: 34162919] (Human)
• T Eichhorn, I Linsberger, L Lauková, C Tripiscian, B Fendl, R Weiss, F König, G Valicek, G Miestinger, C Hörmann, V Weber Analysis of Inflammatory Mediator Profiles in Sepsis Patients Reveals That Extracellular Histones Are Strongly Elevated in Nonsurvivors Mediators of Inflammation, 2021-03-17;2021(0):8395048. 2021-03-17 [PMID: 33790693] (Human)
• AG Vassiliou, C Keskinidou, E Jahaj, P Gallos, I Dimopoulou, A Kotanidou, SE Orfanos ICU Admission Levels of Endothelial Biomarkers as Predictors of Mortality in Critically Ill COVID-19 Patients Cells, 2021-01-19;10(1):. 2021-01-19 [PMID: 33477776] (Human)
• J Ohmes, Y Xiao, F Wang, MD Mikkelsen, TT Nguyen, H Schmidt, A Seekamp, AS Meyer, S Fuchs Effect of Enzymatically Extracted Fucoidans on Angiogenesis and Osteogenesis in Primary Cell Culture Systems Mimicking Bone Tissue Environment Mar Drugs, 2020-09-21;18(9):. 2020-09-21 [PMID: 32967359] (Human)
• J Yu, K Huang, J Pan, J Shen, R Zhan Significance of Serum Angiopoietin-2 in Patients with Hemorrhage in Adult-Onset Moyamoya Disease Biomed Res Int, 2020-08-04;2020(0):8209313. 2020-08-04 [PMID: 32802878] (Human)
• R Zhang, U Rai, NBM Ibrahim, Y Amazouz, J Soo, AL Conroy, S Namasopo, RO Opoka, R Bhargava, MT Hawkes Dysregulation of angiopoietin-Tie-2 axis in ugandan children hospitalized with pneumonia Cytokine, 2020-06-26;133(0):155175. 2020-06-26 [PMID: 32599540] (Human)
• G Varricchi, S Loffredo, L Bencivenga, AL Ferrara, G Gambino, N Ferrara, A de Paulis, G Marone, G Rengo Angiopoietins, Vascular Endothelial Growth Factors and Secretory Phospholipase A2 in Ischemic and Non-Ischemic Heart Failure J Clin Med, 2020-06-19;9(6):. 2020-06-19 [PMID: 32575548] (Human)
• PP Singh, S Bhandari, RK Sharma, N Singh, PK Bharti Association of Angiopoietin Dysregulation in Placental Malaria with Adverse Birth Outcomes Dis. Markers, 2020-01-13;2020(0):6163487. 2020-01-13 [PMID: 32399088] (Human)
• K Shuto, M Mori, C Kosugi, K Narushima, S Nakabayash, T Fujisiro, A Sato, K Hayano, H Shimizu, K Koda Hepatic blood flow by perfusion computed tomography as an imaging biomarker for patients with gastric cancer Oncol Lett, 2019-01-25;17(3):3267-3276. 2019-01-25 [PMID: 30867759] (Human)
• KD Tang, J Liu, PJ Russell, JA Clements, MT Ling Gamma-Tocotrienol Induces Apoptosis in Prostate Cancer Cells by Targeting the Ang-1/Tie-2 Signalling Pathway Int J Mol Sci, 2019-03-07;20(5):. 2019-03-07 [PMID: 30866453] (Human)
• H Murata, T Tsuzuki, T Kido, M Kakita-Kob, N Kida, Y Hisamatsu, H Okada Progestin-induced heart and neural crest derivatives-expressed transcript 2 inhibits angiopoietin 2 via fibroblast growth factor 9 in human endometrial stromal cells Reprod Biol, 2019-03-06;0(0):. 2019-03-06 [PMID: 30852242] (Human)
• JK Wright, K Hayford, V Tran, GM Al Kibria, A Baqui, A Manajjir, A Mahmud, N Begum, M Siddiquee, KC Kain, A Farzin Biomarkers of endothelial dysfunction predict sepsis mortality in young infants: a matched�case-control study BMC Pediatr, 2018-03-23;18(1):118. 2018-03-23 [PMID: 29571293] (Human)
• SJ Higgins, K Ceunynck, J Kellum, X Chen, X Gu, SA Chaudhry, S Schulman, TA Libermann, S Lu, NI Shapiro, DC Christiani, R Flaumenhaf, SM Parikh Tie2 protects the vasculature against thrombus formation in systemic inflammation J. Clin. Invest., 2018-03-05;0(0):. 2018-03-05 [PMID: 29360642] (Mouse)
• Aubin K, Safoine M, Proulx M, Audet-Casgrain M, Côté J, Tetu F, Roy A, Fradette J Characterization of In Vitro Engineered Human Adipose Tissues: Relevant Adipokine Secretion and Impact of TNF-alpha. PLoS ONE, 2015-09-14;10(9):e0137612. 2015-09-14 [PMID: 26367137] (Human)
• McDonald C, Darling A, Conroy A, Tran V, Cabrera A, Liles W, Wang M, Aboud S, Urassa W, Fawzi W, Kain K Inflammatory and Angiogenic Factors at Mid-Pregnancy Are Associated with Spontaneous Preterm Birth in a Cohort of Tanzanian Women. PLoS ONE, 2015-08-06;10(8):e0134619. 2015-08-06 [PMID: 26247200] (Human)
• Ataide R, Murillo O, Dombrowski J, Souza R, Lima F, Lima G, Hristov A, Valle S, Di Santi S, Epiphanio S, Marinho C Malaria in Pregnancy Interacts with and Alters the Angiogenic Profiles of the Placenta. PLoS Negl Trop Dis, 2015-06-19;9(6):e0003824. 2015-06-19 [PMID: 26090803] (Human)
• Ishtiaq S, Edwards S, Sankaralingam A, Evans B, Elford C, Frost M, Fogelman I, Hampson G The effect of nitrogen containing bisphosphonates, zoledronate and alendronate, on the production of pro-angiogenic factors by osteoblastic cells. Cytokine, 2014-11-17;71(2):154-60. 2014-11-17 [PMID: 25461393] (Human)
• Kim Aubin, Caroline Vincent, Maryse Proulx, Dominique Mayrand, Julie Fradette Creating capillary networks within human engineered tissues: Impact of adipocytes and their secretory products Acta Biomaterialia 2015-01-01 [PMID: 25278444] (Human)
• Conroy A, Gelvez M, Hawkes M, Rajwans N, Liles W, Villar-Centeno L, Kain K Host biomarkers distinguish dengue from leptospirosis in Colombia: a case-control study. BMC Infect Dis, 2014-01-20;14(0):35. 2014-01-20 [PMID: 24444080] (Human)
• Giri H, Chandel S, Dwarakanath L, Sreekumar S, Dixit M Increased endothelial inflammation, sTie-2 and arginase activity in umbilical cords obtained from gestational diabetic mothers. PLoS ONE, 2013-12-20;8(12):e84546. 2013-12-20 [PMID: 24376824] (Human)
• Conroy AL, Liles WC, Molyneux ME Performance characteristics of combinations of host biomarkers to identify women with occult placental malaria: a case-control study from Malawi. PLoS ONE, 2011-12-12;6(12):e28540. 2011-12-12 [PMID: 22174834] (Human)
• Conroy AL, Phiri H, Hawkes M, Glover S, Mallewa M, Seydel KB, Taylor TE, Molyneux ME, Kain KC Endothelium-based biomarkers are associated with cerebral malaria in Malawian children: a retrospective case-control study. PLoS ONE, 2010-12-29;5(12):e15291. 2010-12-29 [PMID: 21209923] (Human)
• Lorquet S, Berndt S, Blacher S, Gengoux E, Peulen O, Maquoi E, Noel A, Foidart JM, Munaut C, Pequeux C Soluble forms of VEGF receptor-1 and -2 promote vascular maturation via mural cell recruitment. FASEB J., 2010-05-19;24(10):3782-95. 2010-05-19 [PMID: 20484670] (Human)
• Lash GE, Naruse K, Innes BA, Robson SC, Searle RF, Bulmer JN Secretion of angiogenic growth factors by villous cytotrophoblast and extravillous trophoblast in early human pregnancy. Placenta, 2010-03-24;31(6):545-8. 2010-03-24 [PMID: 20338637] (Human)
• Boneberg EM, Legler DF, Hoefer MM, Ohlschlegel C, Steininger H, Fuzesi L, Beer GM, Dupont-Lampert V, Otto F, Senn HJ, Furstenberger G Angiogenesis and lymphangiogenesis are downregulated in primary breast cancer. Br. J. Cancer, 2009-08-18;101(4):605-14. 2009-08-18 [PMID: 19672262] (Human)
• Bolin M, Wiberg-Itzel E, Wikstrom AK, Goop M, Larsson A, Olovsson M, Akerud H Angiopoietin-1/angiopoietin-2 ratio for prediction of preeclampsia. Am. J. Hypertens., 2009-05-28;22(8):891-5. 2009-05-28 [PMID: 19478794] (Human)
• Ferraro B, Cruz YL, Coppola D, Heller R Intradermal delivery of plasmid VEGF(165) by electroporation promotes wound healing. Mol. Ther., 2009-02-24;17(4):651-7. 2009-02-24 [PMID: 19240696] (Rat)
• Chung I, Han G, Seshadri M, Gillard BM, Yu WD, Foster BA, Trump DL, Johnson CS Role of vitamin D receptor in the antiproliferative effects of calcitriol in tumor-derived endothelial cells and tumor angiogenesis in vivo. Cancer Res., 2009-01-13;69(3):967-75. 2009-01-13 [PMID: 19141646] (Mouse)
• Szarvas T, Jager T, Droste F, Becker M, Kovalszky I, Romics I, Ergun S, Rubben H Serum levels of angiogenic factors and their prognostic relevance in bladder cancer. Pathol. Oncol. Res., 2008-09-20;15(2):193-201. 2008-09-20 [PMID: 18807212] (Human)
• van der Heijden M, van Nieuw Amerongen GP, Koolwijk P, van Hinsbergh VW, Groeneveld AB Angiopoietin-2, permeability oedema, occurrence and severity of ALI/ARDS in septic and non-septic critically ill patients. Thorax, 2008-06-17;63(10):903-9. 2008-06-17 [PMID: 18559364] (Human)

FAQs for Angiopoietin-1 (DY923). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: ANGPT1