Human ACE DuoSet ELISA, 15 Plate Summary
No significant interference observed with available related molecules.
Packaging, Storage & Formulations
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human ACE DuoSet ELISA, 15 Plate
ACE ACE1angiotensin converting enzyme, somatic isoform angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 carboxycathepsin CD143 antigen CD143 DCP DCP1 DCP1angiotensin-converting enzyme dipeptidyl carboxypeptidase 1 Dipeptidyl carboxypeptidase I EC 3.2.1.- EC 184.108.40.206 Kininase II MGC26566 MVCD3 peptidase P testicular ECA Background
ACE and ACE-2, two cell surface proteases, are important regulators of the renin-angiotensin system (RAS), which plays a key role in maintaining blood pressure homeostasis and fluid salt balance in mammals. Because of its location and specificity, ACE plays additional roles in immunity, reproduction and neuropeptide regulation. ACE exists in two isoforms. Somatic ACE comprises two highly similar protease domains whereas germinal ACE comprises a single protease domain. ACE-2 consists of a single protease domain and is an essential regulator of heart and lung function. It is also a cellular receptor for the Spike protein of SARS cornonavirus that causes severe acute respiratory syndrome.
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Publications for ACE/CD143 (DY929)(8)
We have publications tested in 1 confirmed species: Human.
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Publications using DY929
D Lee, JC Park, KS Jung, J Kim, JS Jang, S Kwon, MS Byun, D Yi, G Byeon, G Jung, YK Kim, DY Lee, SH Han, I Mook-Jung Application of QPLEXTM biomarkers in cognitively normal individuals across a broad age range and diverse regions with cerebral amyloid deposition Experimental & Molecular Medicine, 2022-01-20;0(0):. 2022-01-20 [PMID: 35058557] (Human)
V Bánhegyi, A Enyedi, GÁ Fülöp, A Oláh, IM Siket, C Váradi, K Bottyán, M Lódi, A Csongrádi, AJ Umar, M Fagyas, D Czuriga, I Édes, M Pólos, B Merkely, Z Csanádi, Z Papp, G Szabó, T Radovits, I Takács, A Tóth Human Tissue Angiotensin Converting Enzyme (ACE) Activity Is Regulated by Genetic Polymorphisms, Posttranslational Modifications, Endogenous Inhibitors and Secretion in the Serum, Lungs and Heart Cells, 2021-07-06;10(7):. 2021-07-06 [PMID: 34359878] (Human)
S Tejpal, N Sanghera, V Manoharan, J Planas-Igl, CC Bastie, J Klein-Seet Angiotensin Converting Enzyme (ACE): A Marker for Personalized Feedback on Dieting Nutrients, 2020-02-28;12(3):. 2020-02-28 [PMID: 32121233] (Human)
Greulich T, Nell C, Koepke J, Fechtel J, Franke M, Schmeck B, Haid D, Apelt S, Filipovic S, Kenn K, Janciauskiene S, Vogelmeier C, Koczulla A Benefits of whole body vibration training in patients hospitalised for COPD exacerbations - a randomized clinical trial. BMC Pulm Med, 2014-04-11;14(0):60. 2014-04-11 [PMID: 24725369] (Human)
Uri K, Fagyas M, Manyine Siket I, Kertesz A, Csanadi Z, Sandorfi G, Clemens M, Fedor R, Papp Z, Edes I, Toth A, Lizanecz E New perspectives in the renin-angiotensin-aldosterone system (RAAS) IV: circulating ACE2 as a biomarker of systolic dysfunction in human hypertension and heart failure. PLoS ONE, 2014-04-01;9(4):e87845. 2014-04-01 [PMID: 24691269] (Human)
Fagyas M, Uri K, Siket I, Darago A, Boczan J, Banyai E, Edes I, Papp Z, Toth A New perspectives in the renin-angiotensin-aldosterone system (RAAS) III: endogenous inhibition of angiotensin converting enzyme (ACE) provides protection against cardiovascular diseases. PLoS ONE, 2014-04-01;9(4):e93719. 2014-04-01 [PMID: 24690767] (Human)
Michaud A, Acharya K, Masuyer G, Quenech'du N, Gribouval O, Moriniere V, Gubler M, Corvol P Absence of cell surface expression of human ACE leads to perinatal death. Hum Mol Genet, 2013-10-24;23(6):1479-91. 2013-10-24 [PMID: 24163131] (Human)
Miners JS, van Helmond Z, Kehoe PG, Love S Changes with age in the activities of beta-secretase and the Abeta-degrading enzymes neprilysin, insulin-degrading enzyme and angiotensin-converting enzyme. Brain Pathol., 2010-01-12;20(4):794-802. 2010-01-12 [PMID: 20175776] (Human)
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