HMGA2 Antibody [Alexa Fluor® 488]

• Reactivity: Hu, Mu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 488

HMGA2 Antibody [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human HMGA2
  Ser2-Asp109
  Accession # P52926
• Specificity: Detects human and mouse HMGA2 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human HMGB1 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for HMGA2 Antibody [Alexa Fluor® 488]

• BABL
• BABLHMGI-C
• high mobility group AT-hook 2
• High mobility group AT-hook protein 2
• high mobility group protein HMGI-C
• high-mobility group (nonhistone chromosomal) protein isoform I-C
• High-mobility group protein HMGI-C
• HMGA2
• HMGIC
• HMGICSTQTL9
• LIPO

Background

HMGA2, previously known as HMGI-C, belongs to the group of high mobility chromosomal proteins that have the AT-hook DNA-binding motif. It is highly and ubiquitously expressed during embryogenesis. Chromosomal rearrangements of the HMGA2 gene and overexpression are frequently associated with benign and malignant tumors, respectively. Human and mouse HMGA2 share 95% amino acid sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.