Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF
Host: Goat Polyclonal
Species: Hu, Mu, Rt, Ch
Applications: WB, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
HMGA2 encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
8091 |
Alternate Names |
- BABLHMGI-C
- high mobility group AT-hook 2
- High mobility group AT-hook protein 2
- high mobility group protein HMGI-C
- high-mobility group (nonhistone chromosomal) protein isoform I-C
- High-mobility group protein HMGI-C
- HMGICSTQTL9
- LIPO
|
Research Areas for HMGA2
Find related products by research area and learn more about each of the different research areas below.
Cancer