Western Blot: HDAC3 Antibody [NB500-126] - Analysis of HDAC3 Antibody [NB500-126]-Monoclonal Anti-HDAC3 antibody produced in mouse clone 3E11, purified immunoglobulin, buffered aqueous solution
Immunocytochemistry/ Immunofluorescence: HDAC3 Antibody [NB500-126] - HeLa cells were fixed and permeabilized with cold methanol followed by cold methanol:acetone, stained with HDAC3 Antibody diluted at 1:200.
Western Blot: HDAC3 Antibody [NB500-126] - Cell line lysates (Lanes1. HEK-293T; 2. HeLa; 3. K562; 4. COS-7; 5. CHO; 6. NIH-3T3; 7. Neuro-2a; 8. PC-12; 9. NRK) were separated on SDS-PAGE and probed with 1:5,000 Rabbit ...read more
IHC-P: Use human lymph node sections. WB: Use nuclear HeLa human epitheloid carcinoma cells. Predicted molecular weight: 48.8 kDa.
50 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone cetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone acetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.