Hu, Mu, Rt, Ca, Ch, Fe, Pm, XpApplications:
WB, Simple Western, ChIP, ICC/IF, IHC, IHC-P, IPHost:
Hu, Mu, RtApplications:
WB, ICC/IF, IHC, IHC-P, IP, MiArHost:
Species: Hu, Mu, Rt, Po, Bv, Ch, RM
Applications: WB, ChIP, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
WB, ELISA, PA, PAGE, AP
Applications: PAGE, Bioactivity
Applications: WB, ELISA, PA, AP
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone cetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone acetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Bioinformatics Tool for HDAC3
Discover related pathways, diseases and genes to HDAC3. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.