Guanylyl Cyclase alpha 1 Antibody - BSA Free

Western Blot: Guanylyl Cyclase alpha 1 Antibody [NBP2-16770] - Sample (30 ug of whole cell lysate) A: 293T 7. 5% SDS PAGE gel, diluted at 1:1000.

• Reactivity: Hu, Mu, Rt, Po, Bv, Ca
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Guanylyl Cyclase alpha 1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Guanylyl Cyclase alpha 1 Antibody - BSA Free (NBP2-16770) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Guanylyl Cyclase alpha 1. The exact sequence is proprietary.
• Localization: Cytoplasm
• Predicted Species: Mouse (97%), Rat (97%), Porcine (97%), Bovine (96%), Canine (98%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GUCY1A1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 77 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Zebrafish (83%), Japanese Medaka (80%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for Guanylyl Cyclase alpha 1 Antibody - BSA Free

• EC 4.6.1.2
• GC-S-alpha-1
• GCS-alpha-1
• GCS-alpha-3
• guanylate cyclase 1, soluble, alpha 3
• guanylate cyclase soluble subunit alpha-3
• Guanylyl Cyclase alpha 1
• GUC1A3
• GUC1A3GUCA3
• GUCSA3
• GUCSA3GC-SA3
• GUCY1A1
• GUCY1A3
• Soluble guanylate cyclase large subunit

Background

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit, such as alpha-1 (GUCY1A3), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: GUCY1A1
• Uniprot:
  • Q02108(Human)