GTF2IRD1 Antibody [DyLight 755]

• Reactivity: Hu
• Applications: WB, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 755

GTF2IRD1 Antibody [DyLight 755] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 650 and 700 of human general transcription factor 2I repeat domain containing 1 using the numbering given in entry NP_057412.1 (GeneID 9569).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GTF2IRD1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for GTF2IRD1 Antibody [DyLight 755]

• BEN
• CREAM1
• general transcription factor II-I repeat domain-containing protein 1
• General transcription factor III
• GTF2I repeat domain containing 1
• GTF2I repeat domain-containing protein 1
• GTF3GTF2I repeat domain-containing 1
• hMusTRD1alpha1
• muscle TFII-I repeat domain-containing protein 1 alpha 1
• Muscle TFII-I repeat domain-containing protein 1
• MusTRD1
• MusTRD1/BEN
• MUSTRD1general transcription factor 3
• RBAP2WBSCR12binding factor for early enhancer
• Slow-muscle-fiber enhancer-binding protein
• USE B1-binding protein
• WBS
• WBSCR11
• Williams-Beuren syndrome chromosomal region 11 protein
• Williams-Beuren syndrome chromosomal region 12 protein
• Williams-Beuren syndrome chromosome region 11

Background

GTF2IRD1 is encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GTF2IRD1