GRID2 Antibody

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Immunohistochemistry-Frozen: GRID2 Antibody [NBP1-46489] - Axolotl Octavolateralis Nuclei. Image from verified customer review.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-Fr, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

GRID2 Antibody Summary

Immunogen
A synthetic peptide from c-terminal region of human GRID2 (Glutamate receptor delta-2 subunit) conjugated to an immunogenic carrier protein was used as the antigen.
Specificity
Specific for GRID2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GRID2
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:300-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
GRID2 Protein (NBP1-46489PEP)
Reviewed Applications
Read 1 Review rated 5
using
NBP1-46489 in the following applications:

Reactivity Notes

Other species not yet tested.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability.

Alternate Names for GRID2 Antibody

  • B230104L07Rik
  • cpr
  • creeper
  • gluR delta-2 subunit
  • GLURD2
  • GluRdelta2
  • glutamate receptor delta-2 subunit
  • glutamate receptor, ionotropic, delta 2
  • GRID2
  • ho
  • hotfoot
  • Lc
  • lurcher
  • minisatellite 10ac detected by probe MMS10
  • MMS10-AC
  • Ms10ac
  • nmf408
  • SCAR18
  • tpr

Background

Human glutamate receptor delta-2 (GRID2) is a relatively new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. GRID2 is a predicted 1,007 amino acid protein that shares 97% identity with the mouse homolog which is expressed selectively in cerebellar Purkinje cells. A point mutation in mouse GRID2, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This strongly suggests a role for GRID2 in neuronal apoptotic death.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP1-46489
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-Fr, IHC-P

Publications for GRID2 Antibody (NBP1-46489) (0)

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Review for GRID2 Antibody (NBP1-46489) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Other.

Reviews using NBP1-46489:
Filter by Applications
IHC-Fr
(1)
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(1)
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Images Ratings Applications Species Date Details
Immunohistochemistry-Frozen GRID2 NBP1-46489
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reviewed by:
Anonymous
IHC-Fr Other 07/07/2014
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Summary

ApplicationImmunohistochemistry-Frozen
Sample TestedBrain slices
SpeciesOther
CommentsDid not work on lamprey larvae, but worked on all other species with varying fluorescence intensity.

Secondary Antibody

Secondary DescriptionGoat anti-rabbit

Comments

CommentsDid not work on lamprey larvae, but worked on all other species with varying fluorescence intensity.

Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for GRID2 Antibody (NBP1-46489) (0)

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Secondary Antibodies

 

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Additional GRID2 Products

Array NBP1-46489

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Diseases for GRID2 Antibody (NBP1-46489)

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PTMs for GRID2 Antibody (NBP1-46489)

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Anonymous
07/07/2014
Application: IHC-Fr
Species: Other

Bioinformatics

Gene Symbol GRID2
Entrez