GR/NR3C1 Antibody - BSA Free

Immunoprecipitation: GR/NR3C1 Antibody [NBP1-78774] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from NIH3T3 cells. Affinity purified rabbit anti-GR antibody used for IP at 6 mcg/mg lysate. GR was also immunoprecipitated by rabbit anti-GR antibody NBP1-78773 which recognizes a disparate epitope.

• Reactivity: Hu, Mu
• Applications: IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

GR/NR3C1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit GR/NR3C1 Antibody - BSA Free (NBP1-78774) is a polyclonal antibody validated for use in IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen for this product maps to a region between residue 750 and 792 of mouse nuclear receptor subfamily 3 group C member 1 using the numbering given in entry NP_032199 (GeneID 14815).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NR3C1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-10 mcg/mg lysate
• Application Notes: This antibody is not recommended for Western Blot analysis.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GR/NR3C1 Antibody - BSA Free

• GCR
• glucocorticoid receptor
• GR
• GRGCCR
• GRLNuclear receptor subfamily 3 group C member 1
• NR3C1
• nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
• nuclear receptor subfamily 3, group C, member 1

Background

Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocoticoid receptor (GR) and that complex's subsequent association with DNA. All normal mammalian tissues examined to date have been shown to contain glucocorticoid receptor. The corresponding gene for the glucocorticoid receptor is NR3C1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NR3C1
• Uniprot:
  • NP_032199(Mouse)