Gr-1/Ly-6G Antibody (RB6-8C5) [Allophycocyanin]

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Mouse splenocytes were stained with Rat Anti-Mouse B220/CD45R PE‑conjugated Monoclonal Antibody (Catalog # FAB1217P) and either (A) Rat Anti-Mouse Gr‑1/Ly‑6G APC‑conjugated Monoclonal Antibody (Catalog # ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
RB6-8C5
Clonality
Monoclonal
Host
Rat
Conjugate
Allophycocyanin

Order Details

Gr-1/Ly-6G Antibody (RB6-8C5) [Allophycocyanin] Summary

Immunogen
The immunogen for this antibody is Ly-6G (Gr-1, Gr1).
Specificity
Detects mouse Gr-1/Ly-6G. Weak cross-reactivity with Ly-6C is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
Ly6g
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB1037A in the following applications:

  • 5 publications

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Gr-1/Ly-6G Antibody (RB6-8C5) [Allophycocyanin]

  • C6orf23
  • G6D
  • Ly-6C
  • LY6-D
  • Ly6G
  • Ly-6G
  • Ly-6G/Ly-6C (Gr-1)
  • LY6G6D
  • lymphocyte antigen 6 family member G6D
  • MEGT1
  • NG25

Background

The myeloid differentiation antigen Gr-1 is a member of the Ly-6 family, Ly-6G (1). The RB6‑8C5 antibody also reacts weakly with Ly-6C-transfected EL4 cells (2). In the periphery, this antibody specifically recognized granulocytes (3, 4).
  1. Spangrude, G.J. et al. (1988) Science 241:58.
  2. Fleming, T.J. et al. (1993) J. Immunol. 151:2399.
  3. Lewinsohn, D.M. et al.(1987) J. Immunol. 147:22.
  4. Lagasse, E. and I.L. Weissman (1996) J. Immunol. Methods 197:139.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Gr-1/Ly-6G Antibody (FAB1037A)(5)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Flow.


Filter By Application
Flow
(5)
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Showing Publications 1 - 5 of 5.
Publications using FAB1037A Applications Species
SB Fleming, C McCaughan, Z Lateef, A Dunn, LM Wise, NC Real, AA Mercer Deletion of the Chemokine Binding Protein Gene from the Parapoxvirus Orf Virus Reduces Virulence and Pathogenesis in Sheep Front Microbiol, 2017;8(0):46. 2017 [PMID: 28174562] (Flow,, Mouse) Flow Mouse
Pedro Luiz Rosalen Main pathways of action of Brazilian red propolis on the modulation of neutrophils migration in the inflammatory process Phytomedicine, 2016;23(13):1583-1590. 2016 [PMID: 27823622] (Flow,, Mouse) Flow Mouse
Guabiraba R, Besnard A, Menezes G, Secher T, Jabir M, Amaral S, Braun H, Lima-Junior R, Ribeiro R, Cunha F, Teixeira M, Beyaert R, Graham G, Liew F IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice. Mucosal Immunol, 2014;7(5):1079-93. 2014 [PMID: 24424522] (Flow,, Mouse) Flow Mouse
Salvucci O, Jiang K, Gasperini P MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1. Haematologica, 2012;97(6):818-26. 2012 [PMID: 22271895] (Flow,, Mouse) Flow Mouse
Siegemund S, Schutze N, Schulz S, Wolk K, Nasilowska K, Straubinger RK, Sabat R, Alber G Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis. Int. Immunol., 2009;21(5):555-65. 2009 [PMID: 19297659] (Flow,, Mouse) Flow Mouse

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Bioinformatics

Gene Symbol Ly6g