GNB3 Antibody

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: LYOPH

GNB3 Antibody Summary

• Description: Novus Biologicals Rabbit GNB3 Antibody (NB100-98705) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A synthetic peptide from amino acid region 2-50 of human GNB3 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GNB3
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000
  • Immunohistochemistry-Frozen 1:1000
  • Immunohistochemistry-Paraffin 1:1000
  • Western Blot 1:1000
• Control:

  GNB3 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from whole antisera
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the sample size is provided in reconstituted format.

Alternate Names for GNB3 Antibody

• G protein, beta-3 subunit
• GTP-binding regulatory protein beta-3 chain
• guanine nucleotide binding protein (G protein), beta polypeptide 3
• guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3
• guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
• hypertension associated protein
• Transducin beta chain 3

Background

FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GNB3
• Entrez:
  • 2784(Human)
  • 14695(Mouse)
  • 60449(Rat)
• Uniprot:
  • P16520(Human)