G protein alpha Antibody


Western Blot: G protein alpha Antibody [NBP1-31730] - A. 30 ug NIH-3T3 whole cell lysate/extract B. 30 ug JC whole cell lysate/extract 12 % SDS-PAGE G protein alpha Antibody dilution: 1:1000
Immunohistochemistry-Paraffin: G protein alpha Antibody [NBP1-31730] - Paraffin-embedded Colon ca, using antibody at 1:500 dilution.
Western Blot: G protein alpha Antibody [NBP1-31730] - Sample (50 ug of whole cell lysate) A: Mouse brain 10% SDS PAGE; antibody diluted at 1:1000.
Western Blot: G protein alpha Antibody [NBP1-31730] - Sample (30 ug of whole cell lysate) A: Hep G2 B: Raji 10% SDS PAGE; antibody diluted at 1:1000.
Western Blot: G protein alpha Antibody [NBP1-31730] - A. 50 ug rat brain lysate/extract 10 % SDS-PAGE G protein alpha antibody,dilution: 1:1000

Product Details

Reactivity Hu, Mu, Rt, Po, Bv, Ca, XpSpecies Glossary
Applications WB, IHC, IHC-P

Order Details

G protein alpha Antibody Summary

Recombinant protein encompassing a sequence within the center region of human GNAS. The exact sequence is proprietary.
Cell membrane, Peripheral membrane protein, Cell projection, ruffle, Cell membrane, Cell projection, ruffle, || Cell membrane, Peripheral membrane protein
Predicted Species
Porcine (100%), Bovine (100%), Xenopus (97%), Canine (100%). Backed by our 100% Guarantee.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (97%), Xenopus Tropicalis (97%).

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
0.01% Thimerosal
Immunogen affinity purified

Alternate Names for G protein alpha Antibody

  • Adenylate cyclase-stimulating G alpha protein
  • AHO
  • Alternative gene product encoded by XL-exon
  • Extra large alphas protein
  • GNAS complex locus
  • GPSAC20orf45
  • GSP
  • guanine nucleotide binding protein (G protein), alpha stimulating activitypolypeptide 1
  • guanine nucleotide regulatory protein
  • guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
  • MGC33735
  • NESP
  • NESP55
  • neuroendocrine secretory protein
  • PHP1A
  • PHP1B
  • PHP1C
  • POH
  • protein ALEX
  • SCG6
  • secretogranin VI
  • XLalphas


This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contains a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. [provided by RefSeq]


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Gene Symbol GNAS