GNB3 Products

Antibodies
GNB3 Antibody
GNB3 Antibody
NBP1-52107
Species: Hu
Applications: WB, ELISA, IHC
Host: Goat Polyclonal
GNB3 Antibody - BSA Free
GNB3 Antibody - BSA Free
NBP3-35397
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
GNB3 Antibody
GNB3 Antibody
NB100-98705
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Lysates
GNB3 Overexpression Lysate
GNB3 Overexpression Lysate
NBL1-11167
Species: Hu
Applications: WB
Proteins
Recombinant Human GNB3 His Pr ...
Recombinant Human GNB3 His Protein
NBP2-23096
Species: Hu
Applications: PAGE

Description

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.

Bioinformatics

Entrez Mouse
Human
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 2784
Alternate Names
  • G protein, beta-3 subunit
  • GTP-binding regulatory protein beta-3 chain
  • guanine nucleotide binding protein (G protein), beta polypeptide 3
  • guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3
  • guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
  • hypertension associated protein
  • Transducin beta chain 3

Research Areas for GNB3

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction