GMPS Antibody

Western Blot:[NBP3-29817]-Detection of human GMP synthase by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa cells. Antibodies: Affinity purified rabbit anti-GMP synthase antibody used for WB at 0. 04 µg/ml and 1 µg/ml and used for IP at 3 µg/mg lysate. GMP synthase was also immunoprecipitated by rabbit anti-GMP synthase antibody , which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes and 10 seconds.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

GMPS Antibody Summary

• Description: Novus Biologicals Rabbit GMPS Antibody (NBP3-29817) is a polyclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: between 650 and 693
• Assay Type: [Assay Type]
• Sample Volume: [Sample Volume]
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GMPS
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-buffered Saline 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Purity: Affinity purified

Alternate Names for GMPS Antibody

• EC 6.3.5.2
• Glutamine amidotransferase
• GMP synthase [glutamine-hydrolyzing]
• GMP synthase
• GMP synthetase
• guanine monphosphate synthetase
• guanosine 5'-monophosphate synthase
• MLL/GMPS fusion protein

Background

In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GMPS