GITR Ligand/TNFSF18 Antibody Summary
Antibody was raised against purified recombinant human GITR ligand.
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Western Blot 1 ug/ml
- ELISA 1:100-1:2000
- Immunocytochemistry/Immunofluorescence 1:10-1:500
GITRL antibody can be used for the detection of GITRL by Western blot at 1 mg/ml.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for GITR Ligand/TNFSF18 Antibody
- Activation-inducible TNF-related ligand
- GITR Ligand
- GITRLglucocorticoid-induced TNFR-related protein ligand
- Glucocorticoid-induced TNF-related ligand
- hGITRLGITR ligand
- TL6AITR ligand
- tumor necrosis factor (ligand) superfamily, member 18
- tumor necrosis factor ligand superfamily member 18
The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-kappaB and various mitogen-activated protein kinases. The glucocorticoid-induced tumor necrosis factor receptor (GITR) is an emerging member of this family that is expressed on CD4+ CD25+ regulatory T cells and appears to have crucial immune regulation functions. Its ligand GITRL is expressed in endothelial and antigen-presenting cells and can activate NF-kappaB, induce both pro- and anti-apoptotic effects, inhibit the suppressive activity of regulatory T cells, and co-stimulate responder T cells through GITR. Dominant negative forms of NIK and TRAF2 expressed in transfected 293 cells substantially inhibited NF-kappaB activation, suggesting that the GITRL-GITR pathway involves both NIK and TRAF2.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Applications: WB, Flow, Block, CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta)
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Applications: WB, ELISA, ICC/IF
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Applications: Flow, CyTOF-ready, ICC, Neut
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, CyTOF-ready, InhibTFunc
Applications: WB, ICC
Applications: WB, Flow, IHC, CyTOF-ready
Applications: WB, B/N
Applications: WB, Flow, CyTOF-ready, ICC
Publications for GITR Ligand/TNFSF18 Antibody (NBP1-77240) (0)
There are no publications for GITR Ligand/TNFSF18 Antibody (NBP1-77240).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for GITR Ligand/TNFSF18 Antibody (NBP1-77240) (0)
There are no reviews for GITR Ligand/TNFSF18 Antibody (NBP1-77240).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
- 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for GITR Ligand/TNFSF18 Antibody (NBP1-77240) (0)
Additional GITR Ligand/TNFSF18 Products
Bioinformatics Tool for GITR Ligand/TNFSF18 Antibody (NBP1-77240)
Discover related pathways, diseases and genes to GITR Ligand/TNFSF18 Antibody (NBP1-77240). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
PTMs for GITR Ligand/TNFSF18 Antibody (NBP1-77240)
Learn more about PTMs related to GITR Ligand/TNFSF18 Antibody (NBP1-77240).
Research Areas for GITR Ligand/TNFSF18 Antibody (NBP1-77240)
Find related products by research area.
Blogs on GITR Ligand/TNFSF18