Recombinant Human GDF-8/Myostatin Protein Summary
Description |
A recombinant protein corresponding to Human GDF-8/Myostatin |
Preparation Method |
>98% SDS-PAGE |
Protein/Peptide Type |
Recombinant Protein |
Gene |
MSTN |
Purity |
>98%, by SDS-PAGE |
Endotoxin Note |
<0.1 ng/ug |
Applications/Dilutions
Theoretical MW |
27.8 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
Sterile filtered and with no additives. |
Concentration |
Lyoph |
Purity |
>98%, by SDS-PAGE |
Reconstitution Instructions |
Reconstitute with water to a final concentration of 0.1 - 1.0 mg/ml. |
Notes
After reconstituted, dilute further with other aqueous solutions.
Alternate Names for Recombinant Human GDF-8/Myostatin Protein
Background
Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200%) in skeletal muscle mass, similar to those observed in Myostatin knockout mice. Recombinant Human Myostatin Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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