GDF-11/GDF-8 Antibody (743835) [DyLight 488]

• Reactivity: Hu
• Applications: ELISA, B/N
• Clone: 743835
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 488

GDF-11/GDF-8 Antibody (743835) [DyLight 488] Summary

• Immunogen: E. coli-derived recombinant human GDF-11/BMP-11
  Asn299-Ser407
  Accession # O95390
• Specificity: Detects human GDF-11/BMP-11 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with mouse GDF-8 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GDF11
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA
  • Neutralization
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for GDF-11/GDF-8 Antibody (743835) [DyLight 488]

• BMP11
• BMP-11
• bone morphogenetic protein 11
• GDF-11
• GDF-11/GDF-8
• growth/differentiation factor 11
• VHO

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GDF11