Gastrokine 1 Antibody (759821) [Allophycocyanin]

• Reactivity: Mu
• Applications: WB, IHC
• Clone: 759821
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Allophycocyanin

Gastrokine 1 Antibody (759821) [Allophycocyanin] Summary

• Immunogen: E. coli-derived recombinant mouse Gastrokine 1
  Tyr38-Tyr201
  Accession # NP_079742
• Specificity: Detects mouse Gastrokine 1 in direct ELISAs and mouse and rat Gastrokine 1 in Western blots. In Western blots, approximately 10% cross‑reactivity with recombinant human (rh) Gastrokine 1 and no cross-reactivity with rhBlottin is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: GKN1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for Gastrokine 1 Antibody (759821) [Allophycocyanin]

• 18 kDa antrum mucosa protein
• AMP18
• AMP-18
• AMP18BRICHOS domain containing 1
• BRICD1
• CA11
• CA11MGC70354
• FOV
• Foveolin
• Gastrokine 1
• gastrokine-1
• GKN1
• Protein CA11

Background

GKN1, also known as Gastrokine-1, is a 199 amino acid that is approx. 22 kDa, found to be expressed in stomach; has been shown to have mitogenic activity and may be influencing gastric mucosal epithelium. Studies on this protein have shown a relationship with the following diseases and disorders: patent ductus arteriosus, congenital diaphragmatic hernia, respiratory failure, pulmonary hypertension, hernia, gastric cancer, hypertension, gastritis colorectal cancer, and adenocarcinoma. This protein has been linked to positive regulation of cell proliferation, positive regulation of cell division, and digestion pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GKN1