Recombinant Human Galectin-9 His Protein

SDS-Page: Recombinant Human Galectin-9 Protein [NBP1-40399] - Galectin-9, 18.5kDa (168aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE

Product Discontinued

Recombinant Human Galectin-9 His Protein Summary

• Description: A bioactive recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-148 of Human Galectin-9
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAFSGSQAPY LSPAVPFSGT IQGGLQDGLQ ITVNGTVLSS SGTRFAVNFQ TGFSGNDIAF HFNPRFEDGG YVVCNTRQNG SWGPEERKTH MPFQKGMPFD LCFLVQSSDF KVMVNGILFV QYFHRVPFHR VDTISVNGSV QLSYISFQ

• Details of Functionality: The ED50 for this effect is equal or less than2.5 ug/ml. Measured by its ability to agglutinate human red blood cells.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: LGALS9
• Purity: >90%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 18.5 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1 M NaCl
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human Galectin-9 His Protein

• Ecalectin
• GAL9
• gal-9
• galectin 9
• Galectin9
• Galectin-9
• HUAT
• lectin, galactoside-binding, soluble, 9
• LGALS9
• LGALS9A
• MGC117375
• MGC125973
• MGC125974
• Tumor antigen HOM-HD-21
• urate transporter/channel protein

Background

Galectin-9 (Gal-9) is a member of animal lectins that have an affinity to B-galactosides and Forssman pentasaccharide. It is strongly overexpressed in Hodgkin's disease tissue and it might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its consistently associated immunodeficiency. Recombinant Galectin-9 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for Galectin-9 Recombinant Protein (NBP1-40399)(1)

Publication using NBP1-40399

• Cho JL, Roche MI, Sandall B et al. Enhanced tim3 activity improves survival after influenza infection J Immunol 2012-09-15 [PMID: 22875804]

Bioinformatics

• Gene Symbol: LGALS9