Human Galectin-4 ELISA Kit (Colorimetric)

ELISA: Human Galectin-4 ELISA Kit (Colorimetric) [NBP2-60568]

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, Plasma, Cell Culture
• Standard Curve Range: 0.039 - 2.5 ng/mL (example only; lot dependent)
• Sensitivity: 0.07 ng/mL (example only; lot dependent)

Human Galectin-4 ELISA Kit (Colorimetric) Summary

• Description: This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.
• Standard Curve Range: 0.039 - 2.5 ng/mL (example only; lot dependent)
• Sensitivity: 0.07 ng/mL (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Inter-Assay: %CV < 7.40 (example only; lot dependent)
• Intra-Assay: %CV < 4.30 (example only; lot dependent)
• Spike Recovery: 96.00% (example only; lot dependent)
• Kit Type: ELISA Kit (Colorimetric)
• Gene: LGALS4

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Galectin-4 ELISA Kit (Colorimetric)

• Antigen NY-CO-27
• GAL4
• gal-4
• galectin 4
• Galectin4
• Galectin-4
• L-36 lactose-binding protein
• L36LBP
• Lactose-binding lectin 4
• lectin, galactoside-binding, soluble, 4
• LGALS4

Background

Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One member of this family, Galectin-4, also known as Gal-4, L36 or LGALS4 maps to human chromosome 19q13.13 and encodes a 36-37 kDa protein. The Galectin-4 protein is composed of 323 amino acids and contains two homologous carbohydrate recognition domains (CRD) and all amino acids typically conserved in the galectin family. Expression of Galectin-4 correlates with the malignant potential of human hepatocellular carcinoma (HCC) and is differentially regulated depending on cell-cell contact, serum growth factors, cell growth and cell differentiation status. Galectin-4 expression is detected in epithelial cells of the colon, rectum, intestine, and in HT29 and LS174T cell lines. Galectin-4 is underexpressed in colorectal cancer and is preferentially upregulated in cells prone to peritoneal dissemination.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for Galectin-4 ELISA Kit (NBP2-60568)(1)

Publication using NBP2-60568

• Fundora JB, Zhu J, Yanek LR et al. Galectin-4 as a Novel Biomarker of Neonatal Intestinal Injury Digestive diseases and sciences 2021-03-18 [PMID: 33738671]

Bioinformatics

• Gene Symbol: LGALS4