GABA Transporter 2 Antibody - Azide and BSA Free Summary
| Description |
Novus Biologicals Rabbit GABA Transporter 2 Antibody - Azide and BSA Free (NBP2-47147) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee. |
| Immunogen |
A 15 residue synthetic peptide derived from C-terminal domain of rat GAT-2. |
| Specificity |
Reacts with GAT-2 from rat, mouse and human central nervous system. |
| Isotype |
IgG |
| Clonality |
Polyclonal |
| Host |
Rabbit |
| Gene |
SLC6A13 |
| Purity |
Protein A purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- ELISA
- Immunohistochemistry 1:50 - 1:500
- Western Blot 1:200 - 1:5000
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer |
0.1M Tris , 0.1M Glycine and 2% Sucrose |
| Preservative |
No Preservative |
| Concentration |
LYOPH |
| Purity |
Protein A purified |
| Reconstitution Instructions |
Lyophilized powder, reconstituted in distilled water. |
Alternate Names for GABA Transporter 2 Antibody - Azide and BSA Free
Background
GABA is a major inhibitory neurotransmitter and the GABAergic transmission is terminated by the rapid Na+/Cl-dependent uptake of through GABA transporters. There are multiple subtypes of GABA transporters (GAT1, GAT2, GAT3; and betaine GABA transporter (BGT-1). There is ~50% homology between each subtypes. GAT1 and GAT3 have been detected in various parts of the brain while GAT2 is found in many tissues. It appears that GAT1 and GAT3 are involved in distinct GABAergic transmission while GAT2 may be important in non-neural functions. GAT2 is a gamma-amino butyric acid (GABA) transporter. It is a 602 amino acid (85kDa) transmembrane protein
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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