GABA Transporter 2 Products

Description

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl negative channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999).

Bioinformatics

Entrez	171163 Rat
Uniprot	P31646 Rat
Product By Gene ID	6540
Alternate Names	GABA transport protein GAT-2 GAT2Solute carrier family 6 member 13 sodium- and chloride-dependent GABA transporter 2 solute carrier family 6 (neurotransmitter transporter, GABA), member 13

Research Areas for GABA Transporter 2

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Neuroscience