FUS Antibody

Images

 
Western Blot: FUS Antibody [NBP1-57309] - Lane 1 : Human MCF-7 cell lysate K562 Lane 2: Human THP-1 cell lysate Lane 3: Human Hela cell lysate Antibody Dilution: 1.0 ug/ml.
Immunohistochemistry: FUS Antibody [NBP1-57309] - Paraffin Embedded Tissue: Human Intestine Cellular Data: Epithelial cells of intestinal villas Antibody Concentration: 4.0 - 8.0 ug/ml Magnification: 400X
Western Blot: FUS Antibody [NBP1-57309] - HEK293 cell lysate, Antibody Titration: 0.2-1 ug/ml
Western Blot: FUS Antibody [NBP1-57309] - Reccomended Titration: 0.2 - 1 ug/ml Positive Control: HepG2 cell lysate FUS is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells
Western Blot: FUS Antibody [NBP1-57309] - Positive Control: Lane 1: 5 ug mouse brain cytoplasm Lane 2: 5 ug mouse brain nucleus Primary Antibody Dilution : 1:1000 Secondary Antibody : Anti rabbit - IR-dye Secondry ...read more
Immunohistochemistry: FUS Antibody [NBP1-57309] - Human alveolar cell Cellular data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X.
Immunohistochemistry: FUS Antibody [NBP1-57309] - Paraffin Embedded Tissue: Human alveolar cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0 - 8.0 ug/ml Magnification: 400X
Immunohistochemistry: FUS Antibody [NBP1-57309] - Paraffin Embedded Tissue: Human Breast Antibody Concentration: 5 ug/ml

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ca, RbSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

FUS Antibody Summary

Immunogen
Synthetic peptides corresponding to FUS(fusion (involved in t(12;16) in malignant liposarcoma)) The peptide sequence was selected from the N terminal of FUS. Peptide sequence MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FUS
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This is a rabbit polyclonal antibody against FUS and was validated on Western Blot and immunohistochemistry-p
Control
FUS Knockout 293T Cell Lysate

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS & 2% Sucrose.
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for FUS Antibody

  • 75 kDa DNA-pairing protein
  • ALS6
  • amyotrophic lateral sclerosis 6
  • FUS1
  • fused in sarcoma
  • fusion (involved in t(12;16) in malignant liposarcoma)
  • fusion gene in myxoid liposarcoma
  • fusion, derived from t(12;16) malignant liposarcoma
  • fus-like protein
  • heterogeneous nuclear ribonucleoprotein P2
  • HNRNPP2
  • Oncogene FUS
  • Oncogene TLS
  • POMP75
  • RNA-binding protein FUS
  • TLShnRNP-P2
  • Translocated in liposarcoma protein

Background

FUS binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS may play a role in maintenance of genomic integrity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional FUS Products

Bioinformatics Tool for FUS Antibody (NBP1-57309)

Discover related pathways, diseases and genes to FUS Antibody (NBP1-57309). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for FUS Antibody (NBP1-57309)

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PTMs for FUS Antibody (NBP1-57309)

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Research Areas for FUS Antibody (NBP1-57309)

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Blogs on FUS.

Transportin 1 and heterogeneous nuclear ribonucleoprotein D (hnRNPD)
Transportin 1, also known as Karyopherin- beta 2 or Importin- beta 2, is part of the beta -karyopherins family, which consists of importins and exportins responsible for the active transport of proteins between the nucleus and cytoplasm.  Transportin 1 is co...  Read full blog post.

Amyotrophic Lateral Sclerosis Infographic
Amyotrophic lateral sclerosis is a neurological disease which impacts motor neurons that are involved in muscle movement throughout the body. The progressive degeneration of neurons causes weakened muscles and can lead to paralysis. There is no cure f...  Read full blog post.

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Bioinformatics

Gene Symbol FUS