FUS Products

Antibodies
FUS Antibody
FUS Antibody
NB100-565
Species: Hu, Mu, Rt, Po, Bt, Bv, Ca, Pm, Rb, RM
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
FUS Antibody
FUS Antibody
NBP1-89113
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
FUS Overexpression Lysate (Na ...
FUS Overexpression Lysate (Native)
NBL1-10861
Applications: WB
Proteins
Recombinant Human FUS Protein ...
Recombinant Human FUS Protein
NBP1-42462
Species: Hu
Applications: WB, PAGE
FUS Recombinant Protein Antig ...
FUS Recombinant Protein Antigen
NBP1-89113PEP
Species: Hu
Applications: AC
FUS Recombinant Protein Antig ...
FUS Recombinant Protein Antigen
NBP2-52874PEP
Species: Hu
Applications: AC
RNAi
FUS RNAi
FUS RNAi
H00002521-R01
Species: Hu
Applications: RNAi, RNAi SP
FUS RNAi
FUS RNAi
H00002521-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

FUS, fused in sarcoma, encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins. Involved in placental, cardiac, hepatic and embryonic development. NCOA6 is over-expressed in several breast cancer cell lines.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Mouse
Product By Gene ID 2521
Alternate Names
  • fusion (involved in t(12;16) in malignant liposarcoma)
  • POMp75
  • amyotrophic lateral sclerosis 6
  • RNA-binding protein FUS
  • ALS6
  • heterogeneous nuclear ribonucleoprotein P2
  • 75 kDa DNA-pairing protein
  • fusion gene in myxoid liposarcoma
  • Translocated in liposarcoma protein
  • fus-like protein
  • Oncogene TLS
  • POMP75
  • Oncogene FUS
  • HNRNPP2
  • FUS1
  • TLShnRNP-P2
  • fusion, derived from t(12;16) malignant liposarcoma
  • fused in sarcoma

Research Areas for FUS

Find related products by research area and learn more about each of the different research areas below.

Cancer
Neuroscience

Bioinformatics Tool for FUS

Discover related pathways, diseases and genes to FUS. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related FUS Blog Posts

Check out the latest blog posts on FUS.
Transportin 1 and heterogeneous nuclear ribonucleoprotein D (hnRNPD)
Transportin 1, also known as Karyopherin- beta 2 or Importin- beta 2, is part of the beta -karyopherins family, which consists of importins and exportins responsible for the active transport of proteins between the nucleus and cytoplasm.  Transportin 1 is co...    Read more.
Amyotrophic Lateral Sclerosis Infographic
Amyotrophic lateral sclerosis is a neurological disease which impacts motor neurons that are involved in muscle movement throughout the body. The progressive degeneration of neurons causes weakened muscles and can lead to paralysis. There is no cure f...    Read more.
Read more FUS related blogs.