POLQ (NP_006587, 2572 a.a. ~ 2680 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. DGFVQTILGRRRYLPGIKDNNPYRKAHAERQAINTIVQGSAADIVKIATVNIQKQLETFHSTFKSHGHREGMLQSDRTGLSRKRKLQGMFCPIRGGFFILQLHDELLYE
POLQ - polymerase (DNA directed), theta (1C11)
Test in a species/application not listed above to receive a full credit towards a future purchase.
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
In 1x PBS, pH 7.4
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for DNA polymerase theta Antibody (1C11)
DNA polymerase eta
POLHDNA polymerase theta
polymerase (DNA directed), theta
DNA polymerase theta, also referred to as POLQ, is highly expressed in the testes. POLQ has a 2,590 amino acid long isoform that is approximately 290kDa and a shorter 1,786 amino acid long isoform that is approximately 198kDa. POLQ is highly expressed in the testes, plays a role in DNA polymerase activity, and may be implicated in interstrand crosslink repair (ICR). Research on DNA polymerase theta has shown a connection to several diseases and disorders including stomach cancer, malaria, breast cancer, tuberculosis, and meningioma. POLQ has also been shown to have interactions with AP2S1.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.