Genetic Strategies: Knockout Validated: FUS Antibody [NB100-2599] - Western blot shows lysates of HEK293 human embryonic kidney parental cell line and FUS knockout (KO) HEK293 human embryonic kidney cell line. ...read more
Immunohistochemistry-Paraffin: FUS Antibody [NB100-2599] - Section of mouse renal cell carcinoma. Antibody: Affinity purified rabbit anti-FUS used at a dilution of 1:100. Detection: DAB
Immunohistochemistry-Paraffin: FUS Antibody [NB100-2599] - Section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-FUS used at a dilution of 1:500. Detection: DAB staining using anti-rabbit IHC ...read more
Hu, Mu, Rt, Po, Bv, Ca, Mk, Pm, RbSpecies Glossary
The immunogen recognized by this antibody maps to a region between residues 1 and 50 of human fusion (involved in t(12;16) in malignant liposarcoma) using the numbering given in SwissProt entry P35637 (GeneID 2521).
Rat (100%), Porcine (100%), Rabbit (100%), Bovine (100%), Canine (100%), Monkey (100%), Primate (100%). Backed by our 100% Guarantee.
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Panda, Orangutan, Monkey, Gorilla, Chimpanzee and hirteen-lined ground squirrel (100%).
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
TBS and 0.1% BSA
0.09% Sodium Azide
Immunogen affinity purified
Alternate Names for FUS Antibody
75 kDa DNA-pairing protein
amyotrophic lateral sclerosis 6
fused in sarcoma
fusion (involved in t(12;16) in malignant liposarcoma)
fusion gene in myxoid liposarcoma
fusion, derived from t(12;16) malignant liposarcoma
heterogeneous nuclear ribonucleoprotein P2
RNA-binding protein FUS
Translocated in liposarcoma protein
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins. Involved in placental, cardiac, hepatic and embryonic development. NCOA6 is over-expressed in several breast cancer cell lines.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Amyotrophic Lateral Sclerosis Infographic Amyotrophic lateral sclerosis is a neurological disease which impacts motor neurons that are involved in muscle movement throughout the body. The progressive degeneration of neurons causes weakened muscles and can lead to paralysis. There is no cure f... Read full blog post.
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