FUS Antibody (BLR023E)

Images

 
Western Blot: FUS Antibody (BLR023E) [NBP2-76415] - Detection of human and mouse FUS by WB of HeLa, HEK293T, Jurkat, TCMK-1, and NIH 3T3 lysate. Antibody: Rabbit anti-FUS recombinant monoclonal [BLR023E] (NBP2-76415). ...read more
Immunocytochemistry/ Immunofluorescence: FUS Antibody (BLR023E) [NBP2-76415] - Detection of human FUS (red) in FFPE Hep-G2 cells by ICC-IF. Antibody: Rabbit anti-FUS recombinant monoclonal [BLR023E] (NBP2-76415). ...read more
Immunohistochemistry: FUS Antibody (BLR023E) [NBP2-76415] - Section of human breast. Antibody: Rabbit anti-FUS recombinant monoclonal antibody [BLR023E] used at 1:250. Secondary: DyLight® 594- conjugated goat ...read more
Immunohistochemistry-Paraffin: FUS Antibody (BLR023E) [NBP2-76415] - Detection of human FUS in FFPE prostate carcinoma by IHC. Antibody: Rabbit anti-FUS recombinant monoclonal [BLR023E] (NBP2-76415). Secondary: ...read more
Independent Antibodies: Immunoprecipitation: FUS Antibody (BLR023E) [NBP2-76415] - Detection of human FUS by WB of immunoprecipitates from HEK293T lysate. Antibodies: Rabbit anti-FUS recombinant monoclonal ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P, IP
Clone
BLR023E
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

       

Order Details

FUS Antibody (BLR023E) Summary

Immunogen
Immunogen sequence between amino acids 1 and 50
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
FUS
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Immunocytochemistry/Immunofluorescence 1:100 - 1:500
  • Immunohistochemistry 1:100 - 1:500
  • Immunohistochemistry-Paraffin 1:100 - 1:500
  • Immunoprecipitation 20 ul/mg lysate
Application Notes
Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Packaging, Storage & Formulations

Storage
Store at 2 - 8 C / 1 year from date of receipt
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA
Preservative
0.09% Sodium Azide
Purity
Antigen Affinity-purified

Notes

This Product sold under License from Bethyl Laboratories, Inc.

Alternate Names for FUS Antibody (BLR023E)

  • 75 kDa DNA-pairing protein
  • ALS6
  • amyotrophic lateral sclerosis 6
  • FUS1
  • fused in sarcoma
  • fusion (involved in t(12;16) in malignant liposarcoma)
  • fusion gene in myxoid liposarcoma
  • fusion, derived from t(12;16) malignant liposarcoma
  • fus-like protein
  • heterogeneous nuclear ribonucleoprotein P2
  • HNRNPP2
  • Oncogene FUS
  • Oncogene TLS
  • POMP75
  • RNA-binding protein FUS
  • TLShnRNP-P2
  • Translocated in liposarcoma protein

Background

FUS has been identified as a frequent translocation fusion partner of various transcription factors. FUS fusion genes have been shown to be associated with multiple tumor types which include liposarcoma, leukemia, histocytoma, and sarcoma. FUS is a multifunctional RNA-binding protein that associates with the nuclear matrix and Cajal bodies and appears to play a role in splicesome assembly, pre-mRNA splicing, DNA repair, transcriptional regulation and homologous recombination.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for FUS Antibody (NBP2-76415) (0)

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Secondary Antibodies

 

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Bioinformatics Tool for FUS Antibody (NBP2-76415)

Discover related pathways, diseases and genes to FUS Antibody (NBP2-76415). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for FUS Antibody (NBP2-76415)

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Pathways for FUS Antibody (NBP2-76415)

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PTMs for FUS Antibody (NBP2-76415)

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Blogs on FUS.

Transportin 1 and heterogeneous nuclear ribonucleoprotein D (hnRNPD)
Transportin 1, also known as Karyopherin- beta 2 or Importin- beta 2, is part of the beta -karyopherins family, which consists of importins and exportins responsible for the active transport of proteins between the nucleus and cytoplasm.  Transportin 1 is co...  Read full blog post.

Amyotrophic Lateral Sclerosis Infographic
Amyotrophic lateral sclerosis is a neurological disease which impacts motor neurons that are involved in muscle movement throughout the body. The progressive degeneration of neurons causes weakened muscles and can lead to paralysis. There is no cure f...  Read full blog post.

Recombinant Monoclonal Antibodies

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Bioinformatics

Gene Symbol FUS