FPRL1/FPR2 Antibody


Western Blot: FPRL1 Antibody [NLS1878] - WB analysis of FPRL1 in HL-60 cell lysate.
Immunocytochemistry/ Immunofluorescence: FPRL1 Antibody [NLS1878] - FPRL1 antibody was tested in Raw264.7 cells with Dylight 488 (green). Nuclei were counterstained with DAPI (blue).
Immunohistochemistry: FPRL1 Antibody [NLS1878] - IHC analysis of FPRL1 in human kidney cancer using DAB with hematoxylin counterstain.

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-Fr, IHC-P
1.1 mg/ml

FPRL1/FPR2 Antibody Summary

Synthetic peptide made to the 2nd extracellular loop of the human FPRL1 protein (between residues 300-350) [UniProt P25090]
Cell membrane; Multi-pass membrane protein.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
PBS and 30% Glycerol
0.01% Sodium Azide
1.1 mg/ml
Immunogen affinity purified


  • Western Blot 1:1000
  • Immunocytochemistry/Immunofluorescence 1:20-1:75
  • Immunohistochemistry 1:300
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin 1:300
Application Notes
This FPRL1 antibody is useful for Western Blot, Immunocytochemistry/Immunofluorescence, and Immunohistochemistry paraffin embedded sections. In Western Blot, a band is seen ~38 kDa representing FPRL1. In ICC/IF, plasma membrane staining was observed in Raw264.7 cells. In IHC-P, staining was also observed in the plasma membrane of human kidney cancer tissue. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended. Customers have reported success in IF on FFPE mouse kidney tissue, following microwave antigen retrieval. Use in Immunohistochemistry-Frozen reported in scientific literature (PMID 24086560)

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
38 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 1 Review rated 4
NLS1878 in the following applications:

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NLS1878 in the following applications:

Reactivity Notes

Human and mouse. Rat reactivity reported in scientific literature (PMID: 24086560)

Alternate Names for FPRL1/FPR2 Antibody

  • ALXR
  • FMLP-R-I
  • formyl peptide receptor 2
  • Formyl peptide receptor-like 1RFP
  • FPR2
  • FPR2A
  • FPRH1FMLP-related receptor I
  • FPRL1LXA4 receptor
  • HM63
  • HM63FPRH2
  • lipoxin A4 receptor (formyl peptide receptor related)
  • Lipoxin A4 receptor
  • LXA4 Receptor
  • N-formyl peptide receptor 2
  • RFP


FPRL1 (formyl peptide receptor-like-1 or N-formyl peptide receptor 2) is a multi-pass membrane protein receptor belonging to the GPCR1 family and is expressed abundantly in lungs and neutrophils. Among human FPRs and its variants (FPRL1/FPR-like 1 and FPRL2/FPR-like 2), FPRL1 is less efficiently activated by N-fMLP (N-formylmethionylleucylphenylalanine) than FPR and certain agonists which bind FPRL1 with high affinity includes lipoxin A4 eicosanoid, annexin 1, uPAR, the V3 region of the HIV-1 envelope glycoprotein gp120, the acute-phase protein SAA, the 42-amino-acid form of beta-amyloid, human prion peptide, and cathelicidin LL-37. FPRL1 binding to its agonists triggers the activation of intracellular signaling molecules including calcium, PKC isoforms, phospholipases A2 and D, and MAPKs/p38MAPK. FPRL1 activation may result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as leukotriene B4. Expression of FPR1, FPRL1, and FPRL2 has recently been documented to enhance invasive potential of melanoma cells. Moreover, FPRL1 interacts with amyloid beta peptides is implicated in phagocyte attraction to sites of amyloid plaques in Alzheimer's disease.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for FPRL1/FPR2 Antibody (NLS1878)(4)

Reviews for FPRL1/FPR2 Antibody (NLS1878) (1) 41

Average Rating: 4
(Based on 1 reviews)
We have 1 review tested in 1 species: Mouse.

Reviews using NLS1878:
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Images Ratings Applications Species Date Details
reviewed by:
Mouse 12/29/2014


Sample TestedSee PMID 23603910
Special ApplicationsSee PMID 23603910

Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for FPRL1/FPR2 Antibody (NLS1878). (Showing 1 - 4 of 4 FAQs).

  1. I am looking for an FPRL1 antibody that is reactive to mouse only. Does Novus have the antibody in question?
    • To answer your question, unfortunately all our FPRL1 antibodies are polyclonal and would detect both mouse and human formyl peptide receptor-like-1 and we do not have any mouse monoclonal antibody for it.
  2. We would like to know the right target for this antibody.
    • Our antibody with catalogue number NLS1878 was raised against a synthetic peptide derived from the second extracellular loop of the human FPRL1 protein
  3. I am interested in using this antibody for immunohistochemical staining of formalin-fixed rat tissues. I would like to know if this antibody is labeled with any substrate that may aid immunohistochemical staining, or would the HRP Labeled (NLS1878H) or Biotin Labeled (NLS1878B) form be more suitable for my application of interest?
    • Our product NLS1878 is provided as an unlabeled primary antibody. In order to use this antibody for staining in FFPE tissues, you will need to use a directly conjugated anti-rabbit IgG secondary. If you would like to use a directly conjugated primary antibody like NLS1878H or NLS1878B, you will not have to use a secondary antibody for detection. Depending on which detection reagents you are using, that will determine if you need the HRP conjugated or Biotin conjugated antibodies.
  4. May I know if there is a blocking peptide available for this antibody?
    • We do have the blocking peptide available for this item. It is sold under product #NLS1878PEP: Blocking Peptide.

Secondary Antibodies


Isotype Controls

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Contact Information

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Gene Symbol FPR2

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