FoxC1 Antibody (625905) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: WB
• Clone: 625905
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

FoxC1 Antibody (625905) [Alexa Fluor® 647] Summary

• Immunogen: E. coli-derived recombinant human FoxC1
  Gln208-Gln322
  Accession # Q12948
• Specificity: Detects human FoxC1 in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FoxC1 Antibody (625905) [Alexa Fluor® 647]

• ARA
• FKHL7
• FKHL7RIEG3
• forkhead box C1
• forkhead box protein C1
• forkhead, drosophila, homolog-like 7
• forkhead/winged helix-like transcription factor 7
• forkhead-related activator 3
• Forkhead-related protein FKHL7
• Forkhead-related transcription factor 3
• FoxC1
• FREAC3
• FREAC-3
• FREAC3IRID1
• IGDA
• IHG1
• IRID1
• myeloid factor-delta
• RIEG3

Background

Human FoxC1 (forkhead box C1), also called FKHL7 (forkhead-like 7) or FREAC3 (forkhead-related activator 3) is a 553 amino acid (aa) intracellular phosphoprotein that belongs to a large family of nuclear transcription factors that share a common forkhead/winged helix DNA binding domain. FoxC1 is essential for formation of mesodermal tissues; mutations underlie Axenfeld-Rieger malformations of the eye. The human FoxC1 sequence includes a DNA binding domain at aa 77‑168 and an inhibitory domain between aa 268‑245. Phosphorylation within this inhibitory region causes a protein gel mobility shift. Human FoxC1 shares 92% and 91% aa identity with mouse and rat FoxC1, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.