FMO5 Antibody - BSA Free

Immunohistochemistry: FMO5 Antibody - BSA Free [NBP3-46308] - Immunohistochemistry of paraffin-embedded human breast cancer using (FMO5 antibody) at dilution of 1:50

Western Blot: FMO5 Antibody - BSA Free [NBP3-46308] - PC3 cells were subjected to SDS PAGE followed by western blot with (FMO5 Antibody) at dilution of 1:600

• Reactivity: Hu, Mu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

FMO5 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit FMO5 Antibody - BSA Free (NBP3-46308) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: flavin containing monooxygenase 5. (Uniprot# P49326)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FMO5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:500-1:1000
• Theoretical MW: 61 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for FMO5 Antibody - BSA Free

• dimethylaniline monooxygenase [N-oxide-forming] 5
• Dimethylaniline oxidase 5
• EC 1.14.13.8
• flavin containing monooxygenase 5
• FMO 5
• Hepatic flavin-containing monooxygenase 5

Background

FMO5, also known as Dimethylaniline monooxygenase [N-oxide-forming] 5, has a 533 amino acid long isoform that is 60 kDa and a short 285 amino acid isoform that is 32 kDa; is most often expressed in adult and fetal liver, and in contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme. This protein has been studied for its involvement in trimethylaminuria, hearing loss, hepatitis, and atrioventricular septal defect. FMO5 interacts with CYP3A5, CYP3A43, CYP2D6, CYP3A7, and CYP3A4 and it has been linked to Busulfan Q06828 (pharmacodynamics) and drug metabolism - cytochrome P450 pathways .

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FMO5