Ficolin-3 Antibody (FCN334) - BSA Free

• Reactivity: Hu
• Applications: ELISA, IP
• Clone: FCN334
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Ficolin-3 Antibody (FCN334) - BSA Free Summary

• Description: Novus Biologicals Mouse Ficolin-3 Antibody (FCN334) - BSA Free (NBP2-23573) is a monoclonal antibody validated for use in ELISA and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant human H-ficolin
• Epitope: Not determined
• Specificity: Clone FCN334 reacts specifically with H-ficolin. No cross-reaction has been observed with L- or M-ficolin
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FCN3
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunoprecipitation 1:10-1:500
• Application Notes: ELISA: NBP2-23573 reacts with recombinant H-ficolin coated directly onto the microtiter well. A sandwich ELISA for H-ficolin uses NBP2-23573 for both capture and detection. (1)

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 10mM Phosphate (pH 7.4) and 0.5M NaCl
• Preservative: 0.09% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for Ficolin-3 Antibody (FCN334) - BSA Free

• Collagen/fibrinogen domain-containing lectin 3 p35
• Collagen/fibrinogen domain-containing protein 3
• FCNHficolin 3
• ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
• ficolin (collagen/fibrinogen domain-containing) 3 (Hakata antigen)
• ficolin-3
• HAKA1MGC22543
• Hakata antigen
• H-ficolin

Background

H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in humanserum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed bycarbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway bymeans of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDaprotein chains associated in triplet subunits which are again associated in high molecular weightoligomers by means of disulfide bonds at the N-terminal region.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCN3