Ficolin-1 Antibody [DyLight 755]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 755

Ficolin-1 Antibody [DyLight 755] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Ficolin-1
  Gln28-Ala326
  Accession # O00602
• Specificity: Detects human Ficolin-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombinant human (rh) Ficolin-2 is observed and less than 1% cross-reactivity with rhFicolin-3 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: FCN1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Ficolin-1 Antibody [DyLight 755]

• Collagen/fibrinogen domain-containing protein 1
• FCN1
• Fcna
• FCNM
• FCNMficolin-A
• ficolin (collagen/fibrinogen domain containing) 1
• ficolin (collagen/fibrinogen domain-containing) 1
• Ficolin1
• Ficolin-1
• Ficolin-A
• ficolin-alpha
• M-ficolin

Background

M-Ficolin (Ficolin-1) is a non-serum protein that is expressed in leukocytes and lung. M-Ficolin precipitates with mannose-binding lectin (MBL)-associated serine proteases (MASP)-1 and MASP-2, indicating that M-Ficolin forms complexes with MASP-1 and MASP-2, recognizes certain types of bacteria and subsequently activates the lectin pathway (1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCN1