Fibromodulin/FMOD Antibody [FITC]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: FITC

Fibromodulin/FMOD Antibody [FITC] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Fibromodulin/FMOD
  Asp75-Ile376
  Accession # Q06828
• Specificity: Detects human, mouse, and rat Fibromodulin/FMOD in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: FMOD
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for Fibromodulin/FMOD Antibody [FITC]

• Collagen-binding 59 kDa protein
• fibromodulin proteoglycan
• Fibromodulin
• FM
• FMOD
• Keratan sulfate proteoglycan fibromodulin
• SLRR2E
• SLRR2EKSPG fibromodulin

Background

FMOD, also known as Fibromodulin, is a 376 amino acid protein that is 43 kDa, affects the rate of fibrils formation and may have a primary role in collagen fibrillogenesis and regulation of TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Current research is being performed on several diseases and disorders including refractive error, chronic lymphocytic leukemia, myopia, osteoarthritis, arthritis, cleft lip/palate, age related macular degeneration, pseudoachondroplasia, periodontitis, mantle cell lymphoma, chondrodysplasia, diabetic nephropathy, vaginitis, leiomyoma, essential hypertension, atherosclerosis, hypochondrogenesis, and Kniest dysplasia. This protein has also shown an interaction with TGFB1, TGFB2 and TGFB3 in Metalloproteases in connective tissue degradation, metabolism, MPS VI - Maroteaux-Lamy syndrome, disease, keratan sulfate/keratin metabolism, and MPS IIIA - Sanfilippo syndrome A pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FMOD