Fibromodulin/FMOD Antibody (C1) - BSA Free

• Reactivity: Rt
• Applications: ELISA
• Clone: C1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Fibromodulin/FMOD Antibody (C1) - BSA Free Summary

• Immunogen: Immunized with recombinant Rat Fibromodulin/FMOD (Uniprot#: P50609; Gln19-Ile376 (Uniprot#: P50609)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FMOD
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH7.4, 50% glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for Fibromodulin/FMOD Antibody (C1) - BSA Free

• Collagen-binding 59 kDa protein
• fibromodulin proteoglycan
• Fibromodulin
• FM
• FMOD
• Keratan sulfate proteoglycan fibromodulin
• SLRR2E
• SLRR2EKSPG fibromodulin

Background

FMOD, also known as Fibromodulin, is a 376 amino acid protein that is 43 kDa, affects the rate of fibrils formation and may have a primary role in collagen fibrillogenesis and regulation of TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Current research is being performed on several diseases and disorders including refractive error, chronic lymphocytic leukemia, myopia, osteoarthritis, arthritis, cleft lip/palate, age related macular degeneration, pseudoachondroplasia, periodontitis, mantle cell lymphoma, chondrodysplasia, diabetic nephropathy, vaginitis, leiomyoma, essential hypertension, atherosclerosis, hypochondrogenesis, and Kniest dysplasia. This protein has also shown an interaction with TGFB1, TGFB2 and TGFB3 in Metalloproteases in connective tissue degradation, metabolism, MPS VI - Maroteaux-Lamy syndrome, disease, keratan sulfate/keratin metabolism, and MPS IIIA - Sanfilippo syndrome A pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FMOD