FGF-BP Antibody (OTI2B6) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: IHC
• Clone: OTI2B6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

FGF-BP Antibody (OTI2B6) [Alexa Fluor® 532] Summary

• Immunogen: Recombinant protein fragment corresponding to amino acids 24-234 of human FGF-BP (NP_005121) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FGFBP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for FGF-BP Antibody (OTI2B6) [Alexa Fluor® 532]

• 17 kDa heparin-binding growth factor-binding protein
• FGFBP
• FGF-BP
• FGFBP1
• FGF-BP1
• FGFBP-1
• FGFBPFGF-binding protein 1
• fibroblast growth factor binding protein 1
• fibroblast growth factor-binding protein 1
• HBp17
• HBP1717 kDa HBGF-binding protein
• heparin-binding growth factor binding protein

Background

FGFBP1, also known as Fibroblast growth factor-binding protein 1, is a 234 amino acid protein that is approximately 26 kDa, acts as a carrier protein that release fibroblast-binding factors (FGFs) enhancing its mitogenic activity and can be found secreted, in extracellular space and cell membrane. This protein is currently being studied for research on the following diseases and disorders: squamous cell carcinoma, breast cancer, colon cancer, pancreatitis, hypertension, narcolepsy, ataxia, prostatitis, and peritonitis. FGFBP1 has also been shown to have interactions with FGF2, FIBP, NRP2, UBQLN4 and HSPG2 in pathways such as the positive regulation of fibroblast growth factor receptor signaling pathway, positive and negative regulation of cell proliferation, cell-cell signaling and signal transduction.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FGFBP1