FGF-BP Products

Description

FGFBP1, also known as Fibroblast growth factor-binding protein 1, is a 234 amino acid protein that is approximately 26 kDa, acts as a carrier protein that release fibroblast-binding factors (FGFs) enhancing its mitogenic activity and can be found secreted, in extracellular space and cell membrane. This protein is currently being studied for research on the following diseases and disorders: squamous cell carcinoma, breast cancer, colon cancer, pancreatitis, hypertension, narcolepsy, ataxia, prostatitis, and peritonitis. FGFBP1 has also been shown to have interactions with FGF2, FIBP, NRP2, UBQLN4 and HSPG2 in pathways such as the positive regulation of fibroblast growth factor receptor signaling pathway, positive and negative regulation of cell proliferation, cell-cell signaling and signal transduction.

Bioinformatics

Entrez	9982 Human
Uniprot	Q14512 Human NP_005121 Human AAH03628 Human
Product By Gene ID	9982
Alternate Names	FGF-BP1 HBp17 FGF-BP heparin-binding growth factor binding protein 17 kDa heparin-binding growth factor-binding protein fibroblast growth factor-binding protein 1 HBP1717 kDa HBGF-binding protein FGFBPFGF-binding protein 1 FGFBP-1 fibroblast growth factor binding protein 1

Diseases related to FGF-BP

Discover more about diseases related to FGF-BP.

Neoplasms
Tumor Angiogenesis
Malignant Neoplasms
Carcinoma
Malignant Squamous Cell Neoplasm
Pathologic Neovascularization
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Skin Neoplasms
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Mammary Neoplasms
Carcinogenesis
Cell Invasion
Colonic Neoplasms
Dysplasia
Adenocarcinoma
Liver Carcinoma

Pathways for FGF-BP

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Angiogenesis
Wound Healing
Cell Proliferation
Pathogenesis
Secretion
Cell Migration
Rna Interference
Chemotaxis
Localization
Regeneration
Cell Growth
Transport
Protein Phosphorylation
Proteolysis
Regulation Of Gene Expression
Endothelial Cell Proliferation
Cell Cycle Arrest
Embryo Development
Cell Maturation
Sensitization

Research Areas for FGF-BP

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Angiogenesis
Cell Cycle and Replication

PTMs for FGF-BP

Learn more about PTMs related to FGF-BP.

Phosphorylation
Cleavage
Methylation
Ubiquitination

Bioinformatics Tool for FGF-BP

Discover related pathways, diseases and genes to FGF-BP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.