FGF-BP Antibody (OTI2B6) - Azide and BSA Free Summary
| Description |
Novus Biologicals Mouse FGF-BP Antibody (OTI2B6) - Azide and BSA Free (NBP2-45643) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee. |
| Immunogen |
Human recombinant protein fragment corresponding to amino acids 24-234 of human FGFBP1(NP_005121) produced in E.coli. |
| Isotype |
IgG1 |
| Clonality |
Monoclonal |
| Host |
Mouse |
| Gene |
FGFBP1 |
| Purity |
Immunogen affinity purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- Immunohistochemistry 1:150
- Immunohistochemistry-Paraffin
- Western Blot 1:2000
|
| Theoretical MW |
26.1 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles. |
| Buffer |
Lyophilized from PBS (pH 7.3) with 8% Trehalose |
| Preservative |
No Preservative |
| Concentration |
LYOPH |
| Purity |
Immunogen affinity purified |
| Reconstitution Instructions |
we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. |
Alternate Names for FGF-BP Antibody (OTI2B6) - Azide and BSA Free
Background
FGFBP1, also known as Fibroblast growth factor-binding protein 1, is a 234 amino acid protein that is approximately 26 kDa, acts as a carrier protein that release fibroblast-binding factors (FGFs) enhancing its mitogenic activity and can be found secreted, in extracellular space and cell membrane. This protein is currently being studied for research on the following diseases and disorders: squamous cell carcinoma, breast cancer, colon cancer, pancreatitis, hypertension, narcolepsy, ataxia, prostatitis, and peritonitis. FGFBP1 has also been shown to have interactions with FGF2, FIBP, NRP2, UBQLN4 and HSPG2 in pathways such as the positive regulation of fibroblast growth factor receptor signaling pathway, positive and negative regulation of cell proliferation, cell-cell signaling and signal transduction.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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