Feline IL-10 DuoSet ELISA, 15 Plate

• Reactivity: Fe
• Applications: ELISA
• Conjugate: Biotin

Feline IL-10 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: IL10

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Feline IL-10 DuoSet ELISA, 15 Plate

• CSIF
• CSIFMGC126450
• Cytokine synthesis inhibitory factor
• GVHDS
• IL10
• IL-10
• IL10A
• IL-10MGC126451
• interleukin 10
• interleukin-10
• TGIF

Background

Interleukin-10 functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.

Publications for IL-10 (DY736)(6)

Publications using DY736

• KC Clark, FA Fierro, EM Ko, NJ Walker, B Arzi, CG Tepper, H Dahlenburg, A Cicchetto, A Kol, L Marsh, WJ Murphy, N Fazel, DL Borjesson Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome Stem Cell Res Ther, 2017-03-20;8(1):69. 2017-03-20 [PMID: 28320483] (Feline)
• Verbrugghe A, Janssens G, Van de Velde H, Cox E, De Smet S, Vlaeminck B, Hesta M Failure of a dietary model to affect markers of inflammation in domestic cats. BMC Vet Res, 2014-05-04;10(0):104. 2014-05-04 [PMID: 24885092] (Feline)
• Schlecht-Louf G, Mangeney M, El-Garch H, Lacombe V, Poulet H, Heidmann T A targeted mutation within the feline leukemia virus (FeLV) envelope protein immunosuppressive domain to improve a canarypox virus-vectored FeLV vaccine. J Virol, 2013-11-06;88(2):992-1001. 2013-11-06 [PMID: 24198407] (Feline)
• Wood BA, O'Halloran KP, Vandewoude S Development and validation of a multiplex microsphere-based assay for detection of domestic cat (Felis catus) cytokines. Clin. Vaccine Immunol., 2011-01-05;18(3):387-92. 2011-01-05 [PMID: 21209158] (Feline)
• Declue AE, Williams KJ, Sharp C, Haak C, Lechner E, Reinero CR Systemic response to low-dose endotoxin infusion in cats. Vet. Immunol. Immunopathol., 2009-06-11;0(0):. 2009-06-11 [PMID: 19577810] (Feline)
• McEachern JA, Bingham J, Crameri G, Green DJ, Hancock TJ, Middleton D, Feng YR, Broder CC, Wang LF, Bossart KN A recombinant subunit vaccine formulation protects against lethal Nipah virus challenge in cats. Vaccine, 2008-06-02;26(31):3842-52. 2008-06-02 [PMID: 18556094] (Feline)

FAQs for IL-10 (DY736). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: IL10