FAM12B Antibody

Immunohistochemistry-Paraffin: FAM12B Antibody [NBP1-87937] - Staining of human epididymis shows moderate membranous positivity in glandular cells.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

FAM12B Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: EVSWREFMKQHYLSPSREFREYKCDVLMRENEALKDKSSHMFIYISWYKIEHICTSDNWMDRFRNAYVWVQNPLKVLKCHQENSKNSYTESRSFNYIEFHCSMDGYVDSIEDLKMVEPIGN
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: EDDM3B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  FAM12B Protein (NBP1-87937PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for FAM12B Antibody

• epididymal protein 3B
• epididymal secretory protein E3 beta
• epididymal secretory protein E3-beta
• FAM12B
• HE3B
• HE3-BETA
• human epididymis-specific 3 beta
• human epididymis-specific protein 3-beta
• member B (epididymal)
• UNQ6412/PRO21187

Background

Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg.Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen.Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existingcomponents and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes aresynthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come intocontact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster aresynthesized and secreted by epididymal epithelial cells. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EDDM3B