FAM12B Antibody

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Immunohistochemistry-Paraffin: FAM12B Antibody [NBP1-87937] - Staining of human epididymis shows moderate membranous positivity in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

FAM12B Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: EVSWREFMKQHYLSPSREFREYKCDVLMRENEALKDKSSHMFIYISWYKIEHICTSDNWMDRFRNAYVWVQNPLKVLKCHQENSKNSYTESRSFNYIEFHCSMDGYVDSIEDLKMVEPIGN
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EDDM3B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
FAM12B Protein (NBP1-87937PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for FAM12B Antibody

  • epididymal protein 3B
  • epididymal secretory protein E3 beta
  • epididymal secretory protein E3-beta
  • FAM12B
  • HE3B
  • HE3-BETA
  • human epididymis-specific 3 beta
  • human epididymis-specific protein 3-beta
  • member B (epididymal)
  • UNQ6412/PRO21187

Background

Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg.Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen.Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existingcomponents and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes aresynthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come intocontact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster aresynthesized and secreted by epididymal epithelial cells. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol EDDM3B